Postdoctoral Position in Cancer Biology

Location
Maryland (US)
Salary
Salary (commensurate with experience) plus benefits
Posted
October 31 2019
Ref
umessop-umgccc-usda-postdoc 2019
Position Type
Full Time
Organization Type
Academia

An NIH-funded Postdoctoral Research Associate position is available now in Department of Pharmaceutical Sciences at University of Maryland Eastern Shore School of Pharmacy (UMES SOP) for an outstanding candidate interested in cancer biology or translational cancer research. Our laboratory is interested in identification of the RNA risk elements (aberrant RNA splice variants and deregulated microRNAs) in cancers, and aims to study how these oncogenic RNA splice variants or microRNAs contribute to the cancer aggressiveness and drug resistance (see Nature Communications 8:15921, Cancers 10. Pii: E458, Clin. Cancer Res. 21:4970-4984, Mol. Cancer Res. 2019, 10.1158/1541-7786, Prostate Cancer Article ID: 763569). We have a particular focus on the functional impacts of these oncogenic splice variants/microRNAs in activation of PI3K/AKT/mTOR and VEGF signaling pathways. Our work encompasses a wide range of in vitro and in vivo experimental techniques including gene expression, protein biochemistry, signaling transduction, gene knockdown, cell-based functional assays, mouse xenograft, genomics, bioinformatics and interrogation of clinical samples. We are also involved in several genetic/pharmacological efforts to develop novel precision biomarkers and/or therapeutic strategies for cancers. UMES SOP is a highly collaborative environment and our laboratory is involved in collaborations with multiple other research programs within the scientific community including programs in systems biology, high-throughput drug discovery, cancer pathology and pharmacology. This postdoctoral fellow will be trained through a collaborative program by PIs at UMES SOP, University of Maryland Greenebaum Comprehensive Cancer Center (UMGCCC) and Diet, Genomics and Immunology Laboratory at USDA. We are also actively engaged in translating our laboratory-derived findings into clinical setting conducted at the UMGCCC. Highly motivated candidates with a PhD or MD degree and a strong background in molecular biology and cancer biology please send CV to Peter Wang, PhD at bwang@umes.edu

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