Post-doctoral Fellow - NAD Metabolism in Heart Disease

Oklahoma City
See job description.
October 04 2019
Health Sciences
Position Type
Full Time
Organization Type
All Industry

Post-doctoral Fellow - NAD Metabolism in Heart Disease

Posting Number: 000043
Position Type: Scientific
Classification: Ongoing
Status: Full-Time
Department: Cardiovascular Biology - Lee

Job Summary/Basic Function:
The Lee laboratory at the Cardiovascular Biology Research Program (CVB) of the Oklahoma Medical Research Foundation (OMRF) is seeking Postdoctoral Fellow/Staff Scientist who will lead projects to investigate the molecular processes regulating NAD+-dependent pathways in metabolic disorders and cardiac disease. NAD+ is pivotal in cellular metabolism and signaling, and cardiac disease pathogenesis. The candidate will use genetic and pharmacologic approaches to manipulate NAD+ homeostasis, and to evaluate changes in metabolism, cell signaling, cellular senescence, mitochondrial, cardiomyocyte and cardiac functions in vitro and in vivo.

Candidates must be self-motivated, proactive and enthusiastic to their career development. Postdoctoral training program at OMRF (, the Principal Investigator (PI) and the postdoctoral mentoring committee will be committed to training fellows for an independent research career. Staff scientists are also eligible for career development. Candidates will be trained to work independently and contribute intellectually to facilitate a stimulating environment within the research group and research programs at OMRF.

OMRF is an independent, nonprofit biomedical research institute. OMRF has been selected as one of the best research institutions for post-docs in the USA by The Scientist journal. Oklahoma City metropolitan area offers affordable housing, low cost of living, great public schools and numerous recreational activities. The institute offers postdoctoral fellows an exceptional research and training environment with state-of-the-art facilities and outstanding core technology laboratories. Moreover, funds are available for candidates from the PI or OMRF Postdoc Travel Awards to support their attendance at scientific meetings or workshops.

Essential Responsibilities:
1. Actively pursue research under the supervision of PI while developing skills for independent work
2. Organize, analyze, and summarize scientific literature
3. Formulate research questions, design and conduct experiments, and organize and analyze data
4. Communicate scientific data through manuscript writing and presentations
5. Prepare research proposals

Minimum Qualifications:
Successful candidates should have a recent PhD, MD, or MD/PhD degree (within 0-3 years or expect to receive the degree within a year for fellow) in physiology, biochemistry or related biomedical disciplines. First-authored publication(s) in their graduate work is preferred. Prior research experience in mouse models, cardiac physiology, metabolic diseases, proteomics and/or cell biology will be a plus.

Minimum Degree Required:

Work Hours:

Preferred Qualifications:

Physical Demands:

Regularly required to stand, use manual dexterity, talk or hear; Frequently required to walk and reach with hands and arms; occasionally sit; frequently lift and/or move up to 50 pounds; vision abilities include close vision, color vision, depth perception and ability to adjust focus. Potential exposure to fumes, airborne particles, or rodent dander. May work with toxic, caustic chemicals, radioactive materials, liquid nitrogen, human tissue or blood. Potential risk of electrical shock. Occasional exposure to cold 4C, and/or extreme cold -80C from freezers. Noise level is usually moderate.

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