Postdoctoral Fellow/Staff Scientist - Center for Autoimmune Genomics and Etiology

Postdoctoral Fellow/Staff Scientist -

Center for Autoimmune Genomics and Etiology

Genomic technologies (ChIP-seq, EMSA, DAPA, ATAC-seq, DNA methylation, etc.) are being applied in Dr. Harley’s laboratory to reconcile genetic associations with the environmental causes of idiopathic autoimmune disorders with the goal to elucidate mechanisms initiating these pathological processes. The candidate would join a well-funded team that has uncovered unexpected powerful associations of transcription factors with genetic loci, with the goal to establish the genetic mechanisms. The team in place has the strategic, informatic, clinical, and technical expertise to provide strong support for the candidate in addition to the other resources and personnel of the Center for Autoimmune Genomics and Etiology (CAGE). The disorders with direct relevance to this position include lupus, rheumatoid arthritis, multiple sclerosis, type 1 diabetes, inflammatory bowel disease, chronic lymphocytic leukemia, Hodgkin’s disease, and many others (https://www.cincinnatichildrens.org/research/divisions/a/genomics-etiology/team) (Nat Genet. 50:699, 2018). The ideal candidate will have a PhD with a familiarity of genomic molecular laboratory methods (e.g., ChIP-seq, CRISPR-Cas9, EMSA, DAPA, etc.) and be computationally sophisticated. Deep familiarity with genome wide association studies for any complex genetic disease phenotype would be helpful. Preference will be given to applicants with experience with informatic expertise, including genome wide association studies, the analysis of next generation sequence data, large genotyping datasets, and data mining, in general, along with demonstrated scholarly productivity by discovery and publication.

Required: PhD, MD or equivalent doctoral degree.  For Research Associates/Staff Scientists, 3 or more years of relevant postdoctoral research.

Cincinnati Children’s Hospital Medical Center (CCHMC) is a premier pediatric research institution with over 900 diverse and productive faculty members. Here, researchers work collaboratively across specialties and divisions to address some of the biggest challenges we face today in improving child health. A strong network of research support services and facilities, along with institutional commitment to research, push our team of faculty, postdocs and support staff to explore the boundaries of what is possible, leading to significant breakthroughs. We are driven by our mission to improve child health and transform the delivery of care through fully integrated, globally recognized research, education and innovation.

Cincinnati Children's Hospital Medical Center is an Equal Opportunity Employer.