Post-Doctoral Researcher - structure-function studies of ion channels

Location
Pomona, California
Salary
$50,000 - $52,000 + benefits
Posted
September 18 2019
Discipline
Life Sciences
Position Type
Full Time
Organization Type
Academia

Post-Doctoral Researcher - structure-function studies of ion channels

One Research Associate position is available in the Lacroix laboratory at the Western University of Health Sciences (WesternU) in Pomona, California. The Lacroix Laboratory investigates structure-function dynamics and pharmacological mechanisms in mechanosensitive ion channels and develops non-invasive technology to study mechanotransduction in vivo. We use a combination of experimental techniques including protein engineering, patch-clamp electrophysiology, ultrasound stimulation and fluorescence imaging. We are also actively collaborating with other groups on campus and in other institutions. See references [Nat Commun (2018), 9, 2029 and JOVE (2019), 143 doi:10.3791/58781] for examples of recent research from the lab.

The position is available for a highly motivated candidate with a recent PhD in biophysics/biochemistry/pharmacology or any related field. The main task for this position will be to investigate the function of wild-type and mutant ion channels heterologously expressed in mammalian cells using patch-clamp electrophysiology and fluorescence measurements. The candidate will use several configurations including cell-attached, whole cell and excised patch to record macroscopic currents and single channel activity. A demonstrated background in molecular biology and electrophysiology in mammalian cells or other systems (such as two-electrode oocyte voltage clamp) is strongly recommended.

The Lacroix laboratory and WesternU promote diversity and inclusion. The salary compensation for this position matches the NIH guidelines for post-doctoral stipends. WesternU offers competitive benefits and the Pomona area offers affordable housing and a comfortable climate 30 min away from downtown Los Angeles, the San Gabriel Mountains and the pacific coast and its sandy beaches.

To apply, please send a CV, 1-2 page of research experience and career goals along with contact information for 3 references by email to: jlacroix at westernu.edu

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