A postdoc position in breast cancer research

Chicago, Illinois
NIH standard - starting at $50,004/year
August 08 2019
Position Type
Full Time
Organization Type

A postdoc position is immediately available in a breast cancer research lab (Dai Horiuchi, Principal Investigator) at Northwestern University Feinberg School of Medicine and Robert H. Lurie Comprehensive Cancer Center in Chicago.

The focus of the lab is to study the mechanisms of tumor progression in breast cancer (triple-negative breast cancer/TNBC) and to identify novel treatment strategies. To achieve these goals, we utilize a collection of human breast cancer cell lines, preclinical animal models, primary tumor organoids, and high-throughput screening approaches along with state-of-the-art bioinformatics through collaboration with experts in the field. We are determined to help bring basic laboratory findings to clinical testing, and our research involves dynamic interactions with clinicians here at Northwestern Medicine and industry partners.

We are seeking a highly motivated, Ph.D. level researcher with prior in-depth training in (breast) cancer research involving rodent animal models (e.g., transgenic/syngeneic/PDX) as demonstrated by peer-reviewed publications. Fundamental molecular biology/cell biology skills are also required (e.g., cloning, gene-editing, virus-mediated gene expression, and light microscopy). We are particularly interested in identifying a new team member in the following areas of research:

Identification and preclinical validation (including mechanism of drug action studies) of novel therapeutic targets, targeted therapeutic strategies, and their translation to early-stage clinical testing in collaboration with clinicians. - This project requires familiarity with three-dimensional cell culture methods (e.g., Matrigel, spheres, primary organoids, co-culture) and high-throughput high-content screening approaches using BioTek Cytation 5 and Molecular Devices ImageXpress Micro Confocal System. This project may also involve investigating how primary TNBC tumors interact with microenvironmental components.

Overall cancer research at Northwestern is on an exciting, rapid growth phase and provides enormous opportunities for us to positively impact the lives of cancer patients through innovative basic and translational research. Please submit a brief introduction of your academic/research background and current career goals, curriculum vitae, and contact info for three references to Dr. Dai Horiuchi at horiuchilab123@gmail.com. Successful candidates will be contacted via email.

Northwestern University is an Equal Opportunity, Affirmative Action Employer of all protected classes, including veterans and individuals with disabilities. Women, underrepresented racial and ethnic minorities, individuals with disabilities, and veterans are encouraged to apply. Hiring is contingent upon eligibility to work in the United States.


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