Sr. / Principal Research Associate, Analytical Development, mRNA and Raw Material Characterization

Cambridge, MA
July 31 2019
Organization Type
Sr. / Principal Research Associate, Analytical Development, mRNA and Raw Material Characterization

The Role:

Moderna is seeking a Senior/Principle Research Associate Associate for a position based at their Cambridge, MA site. The individual in this role will be a highly skilled, talented and motivated scientist that will be focused on mRNA characterization and development of raw materials release methods. He/she will participate in performing biophysical characterization (UV/TM, DSC & CD) of mRNA, kinetic analysis of mRNA, enzyme kinetic studies and qPCR. The individual will draft IND sections and work with other RAs and Scientists within the Analytical Development and across the Moderna ecosystem. The successful candidate must have a BS with at least 5 years of industry experience, or MS with at least 3 years of industry experience (Analytical, Biochemistry, Molecular Biology, or related science) developing and performing analytical, biochemical, molecular, biophysical and cellular assays.

Here's What You'll Do:
  • Preparation of samples for characterization studies
  • Performing UV/Tm, DSC and CD analysis on mRNA
  • Performing kinetic analysis of RNA degradation
  • Draft regulatory documents
  • Development of enzyme assays
  • Development of advanced qPCR assays for plasmid characterization
  • Accountable for project success and results delivery
  • Record and communicate findings
  • Presentation of results at internal meetings

Here's What You'll Bring to the Table:
  • BS with at least 5 years of industry experience, or MS with at least 3 years of industry experience (Analytical, Biochemistry, Molecular Biology, or related science),
  • Experience in performing biophysical characterization of biologics (UV/TM, DSC and CD)
  • Experience in RNA characterization and comparability analysis
  • Experience in performing kinetic studies on RNA and enzymes
  • Experience in drafting regulatory documents
  • Excellent interpersonal and collaborative skills, and the ability to work independently and effectively in a highly dynamic environment

Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.


Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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