A postdoctoral position is open for highly motivated candidates in the laboratory of Dr. Bokai Zhu at the Aging Institute of University of Pittsburgh School of Medicine. The Zhu lab recently discovered a cell-autonomous mammalian 12h-clock that runs independently from the circadian clock to coordinate 12h oscillations of mRNA surveillance and protein quality control pathways with metabolism (Zhu et al., Cell Metabolism, 2017, Zhu et al., JES, 2018, Pan et al., bioRxiv, 2019). The Zhu lab is currently investigating the transcriptional/post-transcriptional regulation as well as the physiological/pathological functions of the 12h-clock, with an emphasis on its roles in maintaining hepatic metabolic homeostasis and preventing aging-associated diseases. A combination of state-of-the-art computational, biochemical, genetic, cellular, imaging and genomic approaches is currently utilized in the lab. For detailed description of the research performed in Zhu lab, please visit http://www.bzhulab.com
The search is primarily targeted towards scientists who recently finished their PhD. Start date is flexible. Researchers with a passion in systemic and quantitative chronobiology, molecular biology, gene regulation and epigenetics are welcome to apply. Expertise in any of the following areas is highly valued though not required:
• In vivo mouse circadian and hepatic metabolism techniques
• Molecular biology, biochemistry and the field of transcriptional regulation of gene expression, with an emphasis of metabolic regulation of gene expression.
• Expertise in generating and analyzing next-generation sequencing dataset, including but not limited to RNA-Seq, ChIP-Seq, and Chart-Seq.
Pitt med is a national leader in biomedical research. University of Pittsburgh School of Medicine is currently ranked 14th in the category of research by U.S. News and is separately ranked 17th in the Academic Ranking of World Universities list of best medical schools in the world. The medical school’s NIH funding level also ranks fifth in the nation.
To apply, please send a cover letter describing your past training and research interests, a detailed CV and contact information of three referees to Dr. Bokai Zhu at BZHU@pitt.edu.
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