Skip to main content

This job has expired

Senior/Principal Research Associate, Bioassay

Employer
Moderna
Location
Cambridge, MA
Salary
Competitive
Closing date
Mar 8, 2020

View more

Discipline
Life Sciences, Cancer Research
Job Type
Research Scientist
Organization Type
All Industry, Biotech

Job Details

The Role:

Moderna is seeking a Principal Research Associate for a position based at its Cambridge, MA site. The individual in this role will support preclinical and clinical programs through the development and execution of biological and bioanalytical assays, and interface with internal as well as external partnerships (ventures, partners, CROs). This position will contribute to the nonclinical team through the performance and development of laboratory-based assays for both mechanistic and quantitative assessment of novel therapies based on laboratory work. The individual will work with scientists within the nonclinical group and other functional groups to ensure the highest level of quality of these assays. The successful candidate must have experience in assay development ( in-vitro , ex-vivo , biochemical).

Here's What You'll Do:
  • Participate in the drug development project management activities, covering the nonclinical and clinical activities
  • Establish quantitative methods (ELISA, MSD, bDNA, others) and immunogenicity assays (ADA, Nab) for evaluation of PK/TK, safety and efficacy endpoints of nonclinical and clinical studies
  • Establish mechanistic-based functional assays to support the nonclinical team including assay development (in vitro, ex vivo, biochemical, etc.)
  • Responsible for multiple assay-related aspects for platform and development programs
  • Be accountable for all experimental and project related needs assigned


Here's What You'll Bring to the Table:
  • BS with at least 5 years of experience or MS with at least 2 years of experience in biology, immunology, pharmacology, biochemistry, or a related field
  • Knowledge of biochemistry, drug development, pharmacology and regulatory (a plus)
  • Proven hands-on laboratory skills and techniques
  • Familiar with assay qualification/validation guidelines from regulatory agencies and statistical analysis
  • Great ability to troubleshoot assays
  • Exceptional written and oral communication
  • Experience with MSD/ELISA, hybridization-based assays, tissue culture and biochemistry techniques (protein labeling).
  • Proven ability to develop and work independently and to collaborate cross-functionally to accomplish goals in a timely manner
  • Experience with interfacing with CROs
  • Understanding of LIMS


Preferred Qualifications
  • BS with 5-8 years of industry experience or MS with 2-5 years of experience in biology, immunology, pharmacology, biochemistry, or related field
  • Proven experience of assay development and assay troubleshooting; Preferred skills as listed above with immunology and biochemistry-based techniques and assay development


Competencies
  • Effective Communication
  • Flexibility/Adaptability to Change
  • Independence/Teamwork
  • Decision making
  • Applied Learning
  • Innovation


Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to care.com
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)


Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit www.modernatx.com .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

#LI-AG1

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Company

Moderna is a clinical stage pioneer of messenger RNA (mRNA) Therapeutics™, an entirely new in vivo drug technology that directs the body’s cells to produces human proteins, antibodies and novel protein constructs, which are in turn secreted or active intracellularly. Founded in 2011, we are headquartered in Cambridge, Mass. 

Our Team and Mission

We currently have over 500 team members, an exceptional group of scientists and industry professionals who are wholly committed to advancing Moderna’s mission:  deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

Company info
Website

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert