Post Doctoral Research Fellow

Location
Kansas City, Kansas
Salary
50,000
Posted
July 24 2019
Ref
01203244
Position Type
Full Time
Organization Type
Healthcare/Hospital

Post Doctoral Research Fellow

Postdoctoral Research position to study macrophage function in liver disease A postdoctoral fellowship position is available in the Weinman lab and Liver Center at the University of Kansas Medical Center to study macrophage function in inflammatory liver disease. The work will build on recent findings from our lab that alcohol-induced apoptosis of Kupffer cells leads to a cascade of events that orchestrate a time-dependent evolution of liver macrophages toward an anti-inflammatory tolerance phenotype. Future projects will use single cell transcriptome sequencing studies to identify macrophage subtypes, examine roles of apoptotic cell receptors in alcohol-induced inflammatory responses and using novel culture systems to understand the contribution of macrophage-hepatocyte crosstalk in adaptive and maladaptive effects on liver injury. The Weinman lab is located in the state of the art Hemenway Life Science Innovation center opened in 2007 and is part of the KUMC Liver Center. The liver center consists of 34 investigators working on basic and clinical aspects of liver disease and interacts closely with large clinical programs in Hepatology and Liver transplantation. Our lab is adjacent to a number of other NIH-funded labs studying liver-related aspects of lipid metabolism, drug-induced tissue injury, autophagy, extracellular matrix biology, mitochondria function, viral hepatitis, liver carcinogenesis, regeneration and cell growth regulation. A description of our lab research interests can be found at Weinman Lab page. http://www.kumc.edu/school-of-medicine/internal-medicine/clinical-divisions/gastroenterology-hepatology-and-motility/faculty/steven-weinman/weinman-lab.html Work will involve single cell-seq, animal models, cell co-culture techniques and translational studies in humans performed in conjunction with staff from the Liver Center. Candidates must have a recent PhD in immunology, cell biology, biochemistry or a related field with a record of creativity and scientific productivity. Experience with cell biology, single cell sequencing, flow cytometry or bioinformatics is desirable. Salary is commensurate with NIH postdoc scales. To view the complete position description and to apply on-line only go to https://jobs.kumc.edu and search for position J0030411 or use the following link:  http://jobs.kumc.edu/postings/25677 or submit your inquiry and CV to Dr. Steven Weinman, mailto:sweinman@kumc.edu. KUMC is an Affirmative Action, Equal Opportunity Employer.

Candidates must have a recent PhD in immunology, cell biology, biochemistry or a related field with a record of creativity and scientific productivity. Proficiency in molecular and cell biology or cellular immunology techniques is essential.

Experience with cell biology, single cell sequencing, flow cytometry or bioinformatics is desirable