Principal Scientist, Immunology

Cambridge, MA
November 10 2019
Organization Type
The Role:

Moderna is seeking an experienced and motivated immunologist to support the characterization of the immune response against modified mRNA's and delivery systems in preclinical species. He/she will conduct immunogenicity studies from in vitro and in vivo samples including immune cells characterization, cytokines expression, immune genes regulation... In addition, he/she will provide support to establish the regulatory position to enable clinical trials with mRNA.

Here's What You'll Do:
  • Provide scientific guidance and technical expertise for immunological assessment of modified mRNA on cross functional platform teams.
  • Conduct immunogenicity studies to characterize the interaction between immune system and formulated mRNA
  • Develop and implement new assay for Clinical immunology
  • Develop relations with clinical CRO and review clinical immunology results
  • Optimize in vitro assays for improved performance, throughput, capacity, turnaround time, and efficiency.
  • Closely collaborate with members of the immunology and Platform Development teams, and broadly with R&D and therapeutic departments throughout the company.
  • Accountable for screening strategy, execution, interpretation, communication of results, and follow-up assessment.

Here's What You'll Bring to the Table:
  • Ph.D. in immunology with 5 or more years spent overseeing the interaction of the immune system in vaccine field or rare diseases area (in vivo models).
  • Publication of original scientific work in high-quality journals
  • Demonstrated ability to design and execute new experimental approaches
  • Ability to multi-task to meet aggressive timelines and development goals.
  • Candidate will be curious in exploring new path for drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes

Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.


Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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