Principal Research Associate, Drug Product Process Science

Employer
Moderna
Location
Cambridge, MA
Salary
Competitive
Posted
July 18 2019
Ref
R1751
Organization Type
Biotech
Principal Research Associate, Drug Product Process Science

The Role:

We seek a skilled and motivated scientist to work in a tight-knit team executing scaled mRNA formulations and processes. The selected candidate will build-out and successfully run a production operation that executes well established LNP production processes with exceptional attention to detail and business hygiene. We seek applicants that are proactive, enthusiastic, and show a passion for science. Applicants should have exceptional time management and communications skills with strengths in business software analytics and operations. Previous experience with lipid nanoparticles (LNPs), tangential flow filtration, and chemical/biophysical characterization of nanoparticles is preferred. The position will support cross-functional teams across CMC, Research and Development, Production, and Drug Product Analytical Development

Here's What You'll Do:
  • Build from the ground up a formulation manufacturing group that can deliver mid-scale drug product to support pivotal pre-clinical studies.
  • Evaluate and scale existing and novel process modes.
  • Characterize nanoparticle physicochemical properties through collaboration with the Drug Product Analytical team.
  • Work with process owners to tech transfer robust processes into the new group.
  • Build control charting and data analytics of batch productions to look for trends and outliers.


Here's What You'll Bring to the Table:
  • BS in Chemical Engineering, Chemistry, Pharmaceutical Science or related field with 2-5 years or MS with 0-2 years of industry experience in Pharmaceutical or Biotechnology development.
  • Experience in the development of nanoparticle products and processes.
  • Preferred: experience with lipid nanoparticle (LNP) preparation and optimization. Experience with tangential flow filtration.
  • Experience with chemical and biophysical characterization tools for drug delivery systems.
  • Motivated, detail oriented, and shows a passion for science.
  • Comfortable working in a dynamic environment.
  • Flexible, adaptable in collaborations.
  • Ability to manage multiple projects and communicate progress and challenges.
  • Driven to complete assignments.


Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to care.com
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)


Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit www.modernatx.com .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

#LI-AG1

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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