Research Scientist - Cell Engineering for Viral Diseases

San Francisco Bay Area, Menlo Park, California, USA
Competitive salary with full benefits and relocation assistance
July 15 2019
Position Type
Full Time
Organization Type

Research Scientist - Cell Engineering for Viral Diseases

We are seeking enthusiastic scientists to work in the Biosciences Division of SRI International. Candidates will bring contemporary scientific approaches and be motivated to contribute intellectually in a dynamic team environment. The scientists will be mentored for establishing independence in research and contribute to SRI's mission of creating world-changing solutions that make people safer, healthier, and more productive.

We have transformed the T cell into a vector for synthesizing calibrated amounts of engineered proteins in vivo (see NIH Science Highlight, “T-cell biofactories find, fight disease in one fell swoop”; and publication in Advanced Biosystems, 2018), which may be reprogrammed to target different disease cells, e.g. cancer, viral infections, autoimmune disorders. The T-cell Biofactory may lead to a “living drug” that will extravasate to the disease sites, assess the disease burden, synthesize calibrated amount of engineered therapeutic proteins upon stimulation by the diseased cells, and reduce toxicity to the normal cells.

The scientists will use synthetic biology to explore the next generation of cell biofactories (CAR T cells, NK cells, iPSCs) that will activate in response to environmental cues. As part of the team, they will demonstrate the feasibility of using extracorporeal devices to remotely trigger the human immune system against viral infections. The scientists will choose among different target diseases including chikungunya, dengue, HIV, etc. They will write scientific publications and participate in the preparation of grant applications. Located in the San Francisco Bay Area (Menlo Park, CA), this position includes full benefits plus relocation assistance.

About SRI International
From the computer mouse to robotic surgery, cancer treatments, Siri, and more, SRI's 70+ years of innovation have created new industries, billions of dollars in market value, and lasting benefits to society. SRI Biosciences conducts advanced, interdisciplinary research to find solutions to global health problems. We are leaders in health sciences and clinical medicine with focus on next-generation technologies in cell therapies, genetics, pharmaceuticals, bioinformatics, neuroscience, and medical devices. Our partners include government, academic, and biotechnology organizations. As an integrated team, we work with the internal venture division to take therapeutics from Idea to IND® and beyond—from initial discoveries to first in human studies.

PhD in immunology, virology, or related field with more than 3 years of post-degree experience is required. Candidates are expected to have excellent communication, writing, and organizational skills. They will be self-starters with demonstrated ability to independently design and execute laboratory experiments, critically interpret experimental results, and present the data in a clear and concise manner.

How to apply:
Submit CV and cover letter via to job number: 2185BR

For more information, please contact:
Parijat Bhatnagar, PhD
Program Director, Cell-based Medicine
SRI International, Menlo Park, California, USA.
Work: 650-859-4151
Text: 845-401-3427

Please reference the Science Careers posting.

Interested candidates may contact Dr. Bhatnagar in advance for an in-person interview at the American Society for Virology Meeting (ASV2019) at the University of Minnesota.


SRI International is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class.

Similar jobs

Similar jobs