Postdoctoral Associate - Neurodegenerative disease
The Jankowsky lab seeks a postdoctoral fellow to examine the relationship between dementia and myelination. We are studying an endo-lysosomal gene in which non-coding variants influence the risk of cognitive decline in multiple neurodegenerative disease. Unexpectedly, a point mutation in the same gene was found to cause a hypomyelinating disorder, leading us to wonder if there is a connection between lysosome function, oligodendrocyte maturation, and dementia. We have created knock-in and knock-out mice to examine the function of this gene and are poised to take our studies in several exciting new directions, including transcriptional and proteomic profiling and neuro-glial interactions. We seek a motivated candidate who is intellectually and experimentally flexible enough to tackle these new lines of study with us. Researchers will work as part of a team combining mouse genetic engineering, electrophysiology, behavioral testing, and basic biochemistry to elucidate the complex interaction between genetics, aging, and cognitive health.
Applicants should hold (or soon receive) a Ph.D. in neuroscience, genetics, or a related discipline and have a strong background in molecular biology. Experience with genetically engineered mouse models is preferred but not required. Successful applicants should be highly self-motivated, have outstanding experimental skills, and be able to think independently but also work well in a team.
Successful candidates will work in a highly collaborative, small group of scientists with projects spanning diverse facets of neurodegeneration and depression.
The laboratory is located at the main Baylor College of Medicine campus which enjoys a vibrant and collegial scientific environment. BCM itself is located in Houston's Texas Medical Center, a 1,000-acre complex of over 50 independent institutions within easy access.
Houston is the fourth largest city in the US and is home to a diverse international population. The city offers great restaurants, a warm climate, and affordable housing.
The appointment is for an initial term of one year, with the expectation of continued support pending successful progress. The position comes with competitive salary and benefits. International applicants are welcome and will have support of the BCM International Services Office for visa applications. The start date is flexible, and applications will be reviewed on a rolling basis until the position is filled.
Please e-mail inquiries and applications (including contact information for 3 references) to:
Dr. Joanna Jankowsky
Professor of Neuroscience
Baylor College of Medicine
Houston, TX 77030
For more information about the lab and our research, please visit https://www.bcm.edu/research/labs/joanna-jankowsky
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