Scientist, Autoimmunity

Cambridge, MA
August 28 2019
Life Sciences, Biology
Organization Type
Scientist, Autoimmunity

The Role:

Moderna New Venture Labs in Technology Square, Cambridge, MA is seeking an enthusiastic, experienced and motivated bench-level Scientist to help advance Moderna's innovative autoimmune discovery and early pipeline development efforts. Using Moderna's proprietary mRNA platform, this researcher will redirect and modulate cells of the immune system in ways unachievable by other modalities. The successful candidate will possess strong scientific curiosity and a desire to understand and harness immune regulatory pathways for therapeutic benefit, while possessing a solid mix of in vitro and in vivo skills and hands-on experience, preferably with one or more autoimmune models. Knowledge of cellular immunology and experience with lymphocyte analysis is preferred. . Ability to work independently and as part of a small team is essential.

Here's What You'll Do:
  • Bring your passion for science and knowledge of immune regulatory pathways and current immunology literature to identify potential therapeutic targets, and build both in vivo and in vitro assays to test their impact on lymphocyte biology and signaling pathways
  • For the first 12-18 months, the work will be primarily focused in the laboratory whilst the Autoimmunity TA is being established
  • Design, direct and execute in vivo studies in a variety of disease models, internally and through a network of external partners. Work independently and as part of a fast-moving team of researchers to identify disease indications for preclinical candidates and demonstrate Proof of Biology.
  • Work with internal and external partners/stakeholders to test, optimize and advance therapeutic candidates into early development
  • Partner with other members of the Autoimmunity team to build capabilities and identify translatable endpoints in preclinical models

Here's What You'll Bring to the Table:
  • Ideally PhDs with ~2 years' relevant post-doc and/or industry experience. Outstanding PhDs without post-doc or industry experience will also be considered.
  • A strong background in immunology, ideally with current knowledge of functional states of adaptive immunity, including B-cells. Must be motivated to stay on top of the literature.
  • Hands-on experience in both in vivo preclinical disease models, and in vitro cellular techniques including flow cytometry, ELISAs, Westerns, Luminex, MLR or other immunoassay techniques; gene expression by qRT-PCR, and cell culture and cell transduction.
  • Experience with standard programs for data analysis and visualization, basic statistical analysis
  • Attention to detail, scientific versatility, flexibility, results oriented, with effective communication skills and ability to think outside the box.
  • Candidate will embrace our core values. You will be curious in exploring new paths for immune modulation, bold in proposing creative experimental designs and ideas. You will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.

Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.


Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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