Research Associate II - Anatomic Pathology

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate,

patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
A Research Associate II position is available immediately in the laboratory of Dr. Christiane Querfeld, M.D., Ph.D. at Beckman Research Institute of City of Hope.

About the Querfeld Laboratory
Christiane Querfeld, M.D., Ph.D., director of the Cutaneous Lymphoma Program, seeks better treatment options for cutaneous T cell lymphoma (CTCL), a rare form of lymphoma that first appears on the skin but can also spread to lymph nodes and internal organs. City of Hope is one of the few institutions in the country that offers clinical trials to treat cutaneous lymphomas. Dr. Querfeld leads a multidisciplinary team of experts, including medical and radiation oncologists, pioneering treatments for CTCL and its subtypes.

Dr. Querfeld's laboratory investigations are focused on the microenvironment associated with CTCL. She has demonstrated that cancer growth is fostered by the surrounding nonmalignant cells. These observations have led to the

initiation of several targeted and immunologic therapies to restore the immune system and hereby killing the cancerous cells. Examples include a microRNA (miR155) antagomir that inhibits proliferation, an anti-CD47 construct enhancing

macrophage killing and a randomized investigator initiated trial comparing the checkpoint inhibitor anti-PD-L1 with/without the immunomodulatory drug lenalidomide. Her fundamental laboratory research activities involve dissecting

key signaling pathways to advance therapeutic immunologic strategies including mechanisms of resistance.

Key Responsibilities include:

• Utilizing laboratory equipment and established protocols, performs a variety of research experiments. Record and validate results for accuracy and completeness.
  
• May modify protocols.
  
• Write standard operating procedures and reports.
  
• Maintain records of work performed including results and methodology; utilizing records may calculate, graph and compile data.
  
• Develop techniques and expertise in one or more areas relevant to laboratory research project.
  
• Ensure that all laboratory activities are carried out in compliance with safety procedures and guidelines in handling, storage and disposal of materials.
  

Basic education, experience and skills required for consideration:

• Bachelor'sor master's degree in biological sciences, or related discipline.
  
• Two years of post-degree research experience with a bachelor's degree, or
  
• One year of post-degree research experience with a master's degree.
  
• Excellent verbal and written communication skills.
  
• Excellent interpersonal skills.
  

Preferred education experience and skills:

• Experience with Western blots, tissue culture and microscopy, preferred.
  
• Detail oriented, excellent organizational and trouble-shooting skills.
  

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national

origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.