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Postdoctoral Position - Pediatric Neurological Diseases

Postdoctoral Position

Pediatric Neurological Diseases

Postdoctoral fellowship is available to study the molecular and cellular bases of neuronal dysfunction in the pediatric diseases, Glut1 deficiency syndrome (Glut1 DS) and spinal muscular atrophy (SMA). SMA is the most common genetic cause of childhood mortality. Glut1 DS is a significant cause of pediatric epilepsies.  Current projects involve using model mice (J. Clin. Invest. 121: 3029; Neuron, 88: 885; J. Clin. Invest.124: 785; Nat. Commun. 8:14152) to 1) Investigate molecular pathways that link reduced SMN or Glut1 protein to neuronal loss or dysfunction, 2) Identify novel factors that modify or trigger SMA and Glut1 DS and 3) Develop novel treatments for the two diseases.  Applicants must have a published track record in molecular genetics.  Expertise in mouse neurobiology, bioinformatics or electrophysiology is highly desirable.  In addition candidates must be team players, demonstrate initiative and communicate effectively.  The salary for the position is competitive and the academic research environment is internationally recognized as being among the best.  A letter describing your research interests, CV and two letters of reference will constitute an application. Send information to Umrao R. Monani, PhD, 630 W. 168th St., Rm. 5-422, Columbia University Medical Center, New York, NY 10032 or to um2105@columbia.edu [Subject line: Attn: Dr. Umrao R. Monani –PF].

Columbia University is an Equal Opportunity/Affirmative Action Employer, Educator and Contractor, Minorities/Females.

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