POSTDOCTORAL RESEARCH FELLOW - MODULATION OF REGULATORY T CELLS FOR CANCER IMMUNOTHERAPY
- Employer
- Johnson & Johnson
- Location
- Spring House, Pennsylvania
- Salary
- DOE
- Closing date
- Jul 31, 2019
View more
- Discipline
- Other, Other
- Position Type
- Full Time
- Organization Type
- All Industry, Pharma
Janssen BioTherapeutics is seeking a highly motivated individual to identify novel Treg specific targets for cancer immunotherapy
Suppression of anti-tumor immune-response activity by regulatory T cells (Treg) is one of the mechanisms that enables cancer cells to evade host immune surveillance. Modulation of the Treg subsets and/or their function could be a useful cancer immunotherapy strategy. The Postdoctoral Fellow will explore Treg biology in the context of tumor microenvironment and investigate how to target Tregs subsets that drive tumor-induced immune suppression using specific antibodies.
At Janssen, postdoctoral fellows are trained by expert scientists working at the cutting edge of drug discovery. Janssen BioTherapeutics supports a wide range of therapeutic areas including Oncology, Neuroscience, Cardiovascular and Metabolism, Immunology, and Infectious Diseases. The successful candidate will learn from and contribute to an industry-leading drug discovery program that has brought numerous quality therapeutics to patients and significant contributions to human health. They will partner throughout the Janssen R&D organization and participate in cross-functional team discussions, gaining insight into many aspects of biotherapeutic discovery and development. The Postdoctoral Fellow is expected to author papers on their research and present novel findings at scientific conferences.
Key Objective:
To explore Treg biology in the context of tumor microenvironment and investigate how to target Tregs subsets that drive tumor-induced immune suppression using specific antibodies.
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Qualifications
Suitable candidates will have a Ph.D. in Immunology, Oncology, Cell Biology, or a related field. Research experience in one or more of the following areas is preferred:
- Expertise in Treg cell isolation, expansion and functional characterization.
- Background in Immuno-oncology
- Broad knowledge of biochemistry and antibody therapeutics
- Candidates must display an ability to independently design and execute research. In addition to a broad knowledge of immunology and oncology, we are seeking an individual with deep intellectual curiosity, and excellent communication and interpersonal skills
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
Primary Location
United States-Pennsylvania-Spring House-
Organization
Janssen Research & Development, LLC. (6084)
Job Function
R&D
Requisition ID
7536180329
Apply Here: http://www.Click2Apply.net/rz94485gy9m3kw7s
PI110566561
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