Postdoctoral Position in Translational Cancer Biology
The Varadan Laboratory for Translational Systems Biology within the Case Comprehensive Cancer Center is seeking a highly motivated postdoctoral researcher to work within a growing NIH-funded cross-disciplinary team focused on: i) Delineating novel mechanisms underlying the pathogenesis of Barrett’s Esophagus and Esophageal Cancer; ii) Decoding molecular mechanisms contributing to aggressive cancer phenotypes across population groups.
The postdoctoral scholar will be integrated within a nationally-recognized multi-investigator team within the CWRU GI Specialized Program of Research Excellence (GI SPORE), Barrett’s Esophagus Translational Research Network (BETRNet), and P20 Disparities SPORE.
As an integral member of the Case Comprehensive Cancer Center, this unique opportunity will involve engagement with a cross-functional team of clinicians, computational biologists, and basic scientists.
- Doctoral degree in biomedical sciences with sub-specialties in any of Genetics, Cell Biology, Cancer Biology, Biochemistry, Molecular Biology, Pharmacology, Biotechnology or in other relevant fields
- Recent Ph.D graduates and/or PhD candidates graduating in 2019 are encouraged to apply. Current postdoctoral fellows who are eligible for training grants are also particularly encouraged to apply.
- Hands-on expertise in molecular techniques routinely used in cancer research including but not limited to, cell culture, sequencing, generation of genetically modified cell lines, DNA/RNA/protein assessments, in vitro/in vivo assays etc.
- Excellent oral and written communication skills
The Varadan Laboratory is engaged in the integration of large-scale tumor molecular profiles of primary tumor tissues, coupled with experimental validation in preclinical model systems to solve the most pressing challenges in translational cancer research. Our modeling efforts have resulted in the discovery and validation of: novel therapeutic interventions in ovarian cancer (Oncogene, 2017); mechanisms of disease progression in esophageal cancer (Gastroenterology, 2019); and immune modulation in breast cancer (Clinical Cancer Research, 2016). Our goal is to accelerate the discovery and translation of treatment strategies in complex diseases, thus impacting both the prevention and management of aggressive diseases such as cancer.