Postdoctoral Fellow - Cancer Immunology

Duarte, California
February 07 2019
Position Type
Full Time
Organization Type
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

Dr. Mingye Feng's laboratory at the Beckman Research Institute of City of Hope is looking for a talented and highly motivated Postdoctoral Fellow.

Before joining City of Hope, Dr. Feng did his postdoctoral training with Dr. Irving Weissman at Stanford University on cancer immunology. Dr. Weissman's laboratory pioneered studies to understand the roles of tumor-associated macrophages in cancer immunosurveillance and discovered CD47 as a don't eat me signal on cancer cells to protect them from elimination by macrophages. The antibody targeting CD47 is currently in clinical trials for multiple types of human cancers.

Dr. Feng is an awardee of the V Scholar Award from the V Foundation for Cancer Research, the Damon Runyon Dale F. Frey Award for Breakthrough Scientists from the Damon Runyon Cancer Research Foundation, and the K99/R00 Pathway to Independence Award from NIH. His laboratory employs cutting-edge techniques to understand mechanisms of macrophages in cancer immunosurveillance, identify don't eat me signals on various hematopoietic malignant and solider tumor cells, and develop novel cancer immunotherapies targeting metastatic cancer cells. Cancer immunotherapy is one of the most important breakthroughs in the development of cancer treatment approaches. As one of the largest populations of immune cells in human body and the major components of primary tumors and the metastatic sites, macrophages are potentially key effectors mediating tumor immunosurveillance and thus one of the most promising fields in cancer immunology.

Key Responsibilities include:

The successful candidate will utilize a combination of in vitro cell biological, molecular biological and immunological assays and in vivo models to study interactions between cancer cells and macrophages and develop strategies to enable macrophage-mediated cancer immunotherapies. Translational medicine is highly promoted at City of Hope. The successful candidate will have the opportunity to work with clinicians at the Helford Clinical Research Hospital at City of Hope to translate research work in the laboratory to clinically viable reagents and therapies. The position is available immediately.

Basic education, experience and skills required for consideration:
  • A Ph.D. degree in life or biomedical sciences, or a related discipline is required;
  • Strong background in cell biology, cancer biology and/or immunology;
  • Excellent verbal and written skills and integral work ethic.

Additional Information:
  • Please submit your CV, a cover letter, and contact information for three references.
  • For more information regarding Dr. Feng's laboratory (research, publications, etc.) please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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