Postdoctoral Research Associate

Employer
University of Mississippi School of Pharmacy
Location
Oxford, Mississippi
Salary
Salary commensurate with skills and experience
Posted
May 21 2019
Position Type
Full Time
Organization Type
Academia
Job Type
Postdoc

Job Information

Postdoctoral Research Associate to work with structural glycobiology in Dr. Vitor H. Pomin’s laboratory in the Department of BioMolecular Sciences, School of Pharmacy. The position will give opportunities to the researcher to improve skills in methods of multidimensional NMR, isolation and physicochemical analysis of sulfated glycans from natural sources, protein expression and labeling with magnetically active isotopes.

Job Responsibilities

The postdoctoral research associate will work with the most cutting-edge techniques of Nuclear Magnetic Resonance (NMR) spectroscopy used to investigate protein-carbohydrate complexes, especially those formed by sulfated glycans like glycosaminoglycans (GAGs) and sulfated fucans and galactans extracted from marine sources. Post doc will perform advanced NMR experiments like transferred Nuclear Overhauser Effect (trNOE), Saturation Transfer Difference (STD) and Chemical Shift Perturbation (CSP) experiments to investigate the molecular details of sulfated sugars and their protein partners involved intermolecular complexes. Techniques of isolation, purification, 2D NMR and chemical reactions of sulfated glycans will be conducted. In addition, methods to produce isotopically enriched as well as paramagnetically tagged sulfated glycan-derived oligosaccharides and novel approaches used to examine lysine and arginine side chains to identify the binding sites in sulfated glycan-binding proteins such as heparin cofactor II will be performed.

Minimum Education/Experience

Must have a Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, or a related discipline by the time of the appointment. The theoretical and practical experiences in NMR spectroscopy, structural (glyco)biology and protein expression of the applicants will be used for evaluation and ranking by the search committee, and may include minimal or advanced level.  Applications must be submitted through the University of Mississippi's online employment site at https://careers.olemiss.edu.

EEO Statement

The University of Mississippi complies with all applicable laws regarding equal opportunity and affirmative action and does not unlawfully discriminate against any employee or applicant for employment on the basis of race, color, gender, sex, sexual orientation, gender identity or expression, religion, national origin, age, disability, veteran status or genetic information.

Background Check Statement

The University of Mississippi is committed to providing a safe campus community. UM conducts background investigations for applicants being considered for employment. Background investigations include a criminal history record check, and when appropriate, a financial (credit) report or driving history check.