Biologist-In Vivo Incretin Discovery

Indianapolis, Indiana
May 11 2019
Life Sciences
Position Type
Full Time
Organization Type
Job Type
The Lilly Diabetes and Complications Research organization has created a research team focused on discovery and preclinical development of new therapeutics in the areas of Incretin Discovery. The Incretin Discovery team is looking for an in vivo pharmacologist to join team. Do you have an understanding and experience in the development, validation and implementation of in vivo assays with which to develop new therapeutics? Do you have skills to coordinate and perform rodent studies in a team environment to support both small and large molecule projects? Your primary responsibilities will include performing proof-of-concept studies, in vivo assay development and optimization, and execution of studies (both internal and with external partners). You will have the opportunity to work in collaboration with the Incretin and Insulin Discovery groups in a team-oriented environment and to support other groups in the Diabetes and Complications Therapeutic Area with expertise as needed.

Key Objectives/Deliverables
  • Perform acute and chronic in vivo studies (glucose and insulin tolerance tests, etc.) including animal handling, blood and biopsy collection, measurement of body weight and food intake as well as test article formulation and administration by oral gavage and subcutaneous, intravenous, and intramuscular injection.
  • Assessment of meal patterning, body composition analysis, respiratory quotient and other parameters of body weight regulation
  • Perform small animal surgical procedures including, but not limited to, rodent catheter and mini pump implantation.
  • Requirement for accurate record keeping, independent data analysis, and reporting of data in written and oral formats.

Company Overview

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Basic Qualifications

  • Associate's Degree with at least 1 year of relevant in vivo/lab experience post education or
  • Bachelor or Master Degree with relevant training, background or experience
  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position.

Additional Information

  • Flexible scheduling is a requirement. The position is full-time (40 hrs/wk), but not all regularly scheduled work hours will occur Mon-Fri from 8 AM-4:45 PM. There is a requirement to work after-hours or on weekends on occasion.
  • The position level will be commensurate with the candidate's experience. The position is governed by regulations including OSHA, AAALAC, OLAW and NRC - compliance to all applicable regulations is mandatory.
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.

Additional Skills/Preferences

  • Laboratory research experience preferred
  • Experience in handling, dosing, sample collection in small laboratory animals
  • Familiar with setting up and running biochemical assays (protein, glycogen, enzyme assays, etc.), running ex vivo primary tissue assays and with aspects of protein analysis (SDS-PAGE gels and western blotting).
  • Experience and willingness to work with radioisotopes, chemical, and biological hazards.
  • Proven ability to work in flexible, team-oriented environment.
  • Experience in diabetes and/or metabolic diseases is preferred.
  • Oral/written communication/listening skills in English are essential.
  • Strong relationship-building and interaction skills with peers and management.
  • Bachelors or Master's degree in Biology or related field

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