Postdoctoral/Research Associate—Gene regulation in the immune systems
One of the important questions in immunology is how immune effector cells acquire the ability to express a set of genes that enable them to carry out specialized immune functions. Our lab studies transcriptional and epigenetic regulation of the expression of genes important in the normal and diseased immune system (Immunity, 2013, 39: 97-110; JI, 2015, 194: 4328-38; J Allergy Clin Immunol, 2018; 10.1016/j.jaci.2017.10.043). We are seeking a Postdoctoral/Research Associate to study how master transcription factors regulate the set of genes during differentiation of progenitors/precursors into immune effector cells and how immune genes in the differentiated effector cells detect signal inputs triggered by extracellular immunological stimuli and convert them into transcriptional outputs. Candidates should have a recent Ph.D. degree in molecular immunology or molecular biology. Experience with molecular cloning, RNA and DNA isolation, RT-qPCR and cell culture is required. Experience with CRISPR, shRNA knockdown, ChIP, and western blot, Next Generation Sequencing and bioinformatic analysis is highly desired. Please send curriculum vitae and three references to:
Hua Huang M.D. Ph.D.
Department of Biomedical Research, National Jewish Health, Department of Immunology and Microbiology, University of Colorado School of Medicine, 1400 Jackson Street, K511a, Denver, CO 80206. email@example.com