Associate Director/ Director, Antigen Design & Selection

Cambridge, MA
May 03 2019
Life Sciences, Biology
Organization Type
Associate Director/ Director, Antigen Design & Selection

The Role:

Moderna Infectious Disease, is seeking an exceptionally talented and highly motivated scientific leader, with a broad skill base in computational and structural biology, bioinformatics and protein biochemistry, to lead the antigen selection and design team. They will be part of a highly collaborative, multi-disciplinary, and fast-paced team that is translating Moderna's mRNA technology into an exceptionally broad portfolio of vaccines and therapeutics against infectious diseases. The successful applicant will deploy his/her extensive expertise in protein modelling and characterization, to lead a small team of computational biologists and protein biochemists, to develop novel antigens or therapeutics proteins that can be successfully encoded via Moderna's mRNA technology. This is a unique opportunity to work in an innovative environment on a truly transformative infectious diseases platform.

Here's What You'll Do:
  • Lead, reinforce and supervise a small team of scientists/RAs to design and characterize novel antigens for Moderna's vaccines and therapeutics against infectious disease targets
  • Identifying and nurturing relationships with CROs and leading academic centers with state-of-the art capabilities for protein design and characterization
  • As a member of the Research Leadership team, help shape the overall portfolio of approaches and problem-solve their technical execution

Here's What You'll Bring to the Table:
  • PhD in Biochemistry, Biology, Molecular Biology, Biophysics, Structural biology
  • 5 years of experience in antigen/protein design and characterization.
  • Proven record of discovery of several vaccines with successful proof-of-concept studies in animal models and, ideally, in human studies
  • Track record of leading projects through to IND or other equivalent early clinical milestone
  • Several years of supervisory experience
  • C andidate will be curious in exploring new path for drug discovery, bold in proposing creative experimental designs and ideas. Will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes

Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Why join Moderna

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.


Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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