Sr. Scientist, Nonclinical Statistics

Employer
Moderna
Location
Cambridge, MA
Salary
Competitive
Posted
May 03 2019
Ref
R1367
Discipline
Life Sciences, Biology
Organization Type
Biotech
Sr. Scientist, Nonclinical Statistics

The Role:

Moderna is seeking a talented and highly motivated biostatistician with a solid background in statistics, excellent communication skills, and a deep interest in drug discovery and development. The successful applicant will collaborate with biologists, chemists, engineers, and computational scientists on a wide range of research activities across the Research Platform, Technology Development, and Therapeutic Areas. This will include rodent/primate animal studies, in vitro assays, high throughput screens, NanoString/proteomics/lipidomics platforms, and Chemistry Manufacturing and Control (CMC) processes. (S)he will also be directly involved in promoting and maintaining high standards of statistical rigor in experimental design and data analysis across the organization. The level of the position will be based on the experience of the successful candidate.

Here's What You'll Do:
  • Contribute to project tasks from statistics perspective, including study design and sample size determination, authoring/reviewing statistics section in protocols, analyzing data from studies, and presenting statistical analysis to a wide audience
  • Work collaboratively with cross-functional teams to ensure rigorous design and appropriate statistical analysis are applied to all in vivo pharmacology studies, in vitro studies, and high throughput screens
  • Help develop and validate new biological and biophysical assays
  • Develop and apply appropriate statistical analysis methods to solve the needs and challenges specific to developing mRNA therapeutics
  • Oversee statistical work by CRO and ensure quality deliverables with respect to key performance indicators, metrics, deliverables and timelines
  • Independently conduct analyses suggested by the data and propose new statistical approaches to improve the efficiency and sensitivity of study results
  • Ensure statistical integrity of deliverables; provide statistically sound scientific methodology input to meet project objectives and regulatory statistical and data requirements.
  • Communicate findings internally and externally. Contribute to scientific and strategy discussions to advance and enhance the scientific platform and product candidates. Author/review scientific publications.


Here's What You'll Bring to the Table:
  • M.S. or Ph.D. in Biostatistics, Statistics, or a related field is preferred. Outstanding candidates with B.S. in statistics and solid experience will be considered.
  • Scientific and technical expertise in the following:
    • Predictive and inferential statistics, including design of experiments, predictive modeling, parametric and non-parametric techniques
    • Proficiency in at least one of: R, Python, JMP, SAS
    • Understanding and/or experience in drug discovery and development
  • Strong written and oral communication skills to convey statistical concepts and analyses to non-statisticians in a clear and understandable way
  • Positive team building and teamwork skills: innate ability to influence, lead and inspire people, within function and beyond functional/company boundaries


Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to care.com
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays


Why join Moderna Therapeutics

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit www.modernatx.com .

Our Mission:

Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.

#LI-AG1

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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