Research Associate I

Duarte, California
April 18 2019
Position Type
Full Time
Organization Type
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
A Research Associate I position is available to work on Preclinical Drug Development. The focus of this position is be protein production. Under the direct supervision of the Principal Investigator, or designee, the Research Associate I performs a variety of routine and increasingly complex research experiments.

Key Responsibilities include:

  • Utilizing laboratory equipment and established protocols, performs a variety of research experiments. Records and validates results for accuracy and completeness.
  • May modify protocols.
  • Write standard operating procedures and reports.
  • Maintains records of work performed including results and methodology; utilizing records may calculate, graph and compile data.
  • Develops techniques and expertise in one or more areas relevant to laboratory research project.
  • Ensures that all laboratory activities are carried out in compliance with safety procedures and guidelines in handling, storage and disposal of materials.

Basic education, experience and skills required for consideration:

Bachelor's degree in biological sciences.
  • 0-2 years of research/laboratory experience.
  • Excellent verbal and written communication skills. Excellent interpersonal skills.

Preferred education, experience and skills:
  • Versed in protein purification methods (Affinity, SEC, IEX), analysis (e.g., SDSPAGE);
  • Experience with cell culture (E. coli and CHO a must, yeast and insect desirable).
  • Experience with SPR and other biophysical methods desirable. Must have excellent communication and organizational skills. Is expected to work as part of a team.
  • Hands-on experience in cell culture (different cancer cell lines) and cell assay.
  • Excellent computer skills.
  • Protein expression characterization: SDS-PAGE, Western blots, etc.
  • Hands-on experience in cell culture (different cancer cell lines) and cell assay.
  • Excellent computer skills.
  • Hands-on experience in mice immunization, blood collection and B cell isolation, is a plus.
  • Hands-on experience in antibody screening from hybridomas, is a plus.
  • Hands-on experience in ELISAs, is a plus.
  • Experience in phage or yeast display techniques, is a plus.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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