Postdoctoral Fellow - Leukemia Cell Survival

Duarte, California
March 21 2019
Position Type
Full Time
Organization Type
Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions. We invite you to also view our current openings.

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Postdoctoral Fellow. Acute lymphoblastic leukemia develops in the bone marrow. The leukemia cells can become resistant to drug treatment because they obtain support for their growth and survival from stromal cells in this environment. This lab studies the molecules and mechanisms that are responsible for this type of drug resistance development.

Key Responsibilities include:

For this position we are particularly interested in someone with a PhD and expertise in cell biology to study mechanisms of lysosomal programmed cell death. We work with leukemia in tissue co-culture with stromal cells, cell imaging, retroviral or lentiviral transduction, Cas/CRISPR knockout, FACS, and mice. Candidates who are interested in following an academic career path, are self-motivated and enjoy the complexity of biological systems are especially encouraged to apply.

Basic education, experience and skills required for consideration:
  • Ph.D. in cell biology or related field.
  • Experience in working with hematopoietic cells in tissue culture, imaging cells.

Preferred education experience and skills:
  • Expertise in glycobiology is an advantage but not required.

Additional Information:
  • The location of our lab at the Monrovia Campus of the Beckman Research Institute within the Department of Systems Biology provides many opportunities to interact with others who study leukemias.
  • Our lab also has ongoing collaborations in the area of glycobiology with scientists at the Institute for Glycomics, Griffith University, Australia.
  • For more information, please visit Dr. Heisterkamp's lab here .
  • Please include an updated CV, a 1-page cover letter describing your current position, your reasons for applying and contact details of three recent referees as a single PDF.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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