Scientist-ADME

Employer
Lilly
Location
Indinapolis, Indiana
Salary
Competitive
Posted
March 20 2019
Ref
48033BR
Discipline
Life Sciences
Position Type
Full Time
Organization Type
Pharma
Job Type
Other
The Biotechnology Research/ADME group is responsible for evaluating the preclinical pharmacokinetics and disposition of therapeutic proteins/peptides and monoclonal antibodies. Do you have experience in the development and validation of mass spectrometry based assays? Have you worked with development of immunoassays and ligand binding assays? We are looking for passionate researchers with this experience to join our team. You will collaborate with toxicology, discovery biology, protein engineering and multiple therapeutic areas to help identify and characterize optimal therapeutic entities to advance to clinical testing. The group is growing capabilities in analytical, cell biology and PK/PD to more fully characterize factors influencing the absorption and disposition of biologic therapeutics. You will enjoy an exciting and impactful career at a company continually striving to improve the lives of patients around the world.
Key opportunities:
  • Develop/validate mass spectrometry methods for measurement of therapeutic peptides, proteins, and target/biomarker concentrations in relevant animal models.
  • Evaluate technologies and equipment to enable analytical method development.
  • Apply immunological reagents to improve MS method development.
  • Participate in cross-functional working groups supporting new molecule SAR.
Key Objectives/Deliverables:
  • Mass Spectrometry analytical method development to support PK/PD studies.
  • Work with CROs for method transfer/troubleshooting.
  • Collaborate with biology, toxicology, and clinical research
  • Excellent communication skills, networking, and problem solving capabilities.


Company Overview

At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Basic Qualifications

  • Bachelor's degree in biology, chemistry or related discipline
  • Qualified candidates must be legally authorized to be employed in the United States. Lilly does not anticipate providing sponsorship for employment visa status (e.g., H-1B or TN status) for this employment position


Additional Information

  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.


Additional Skills/Preferences

  • Master's degree in biology, chemistry or related discipline
  • Experience with various modes of sample preparation (solid phase extraction, immunoprecipitation, liquid/liquid extraction.
  • Experience with robotic sample handling
  • Experience with chromatography of biomolecules
  • Direct experience with triple quadrupole and high-resolution MS platforms
  • Strong written and verbal communication skills
  • Familiarity with handling of radioisotopes

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