Bacterial Pathogenesis Postdoctoral Position

Bacterial Pathogenesis Postdoctoral Position

A postdoctoral researcher position is available in the laboratory of Carlos J. Orihuela in the Department of Microbiology at the University of Alabama at Birmingham (UAB). We are seeking an enthusiastic and highly motivated scientist to join an NIH funded research program focused on the molecular and immunological basis of organ damage during invasive infection by Streptococcus pneumoniae. The successful candidate will have access to cutting-edge animal, in vitro, microscopic, and ‘omics-based research models to dissect the host-pathogen interactions that are responsible for disease. Hired individuals will benefit from the highly vibrant and world class Streptococcal research community that is present at UAB. They will also participate in ongoing collaborations within and outside the United States. UAB is consistently ranked among the top US universities for postdoctoral training. The hired fellow will have access to considerable training resources in preparation for a successful independent career in academia or industry.

RELEVANT PUBLICATIONS:

1: Gonzalez-Juarbe N, et al. Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia. Sci Rep. 2018 Apr 11;8(1):5846.

2: Shenoy AT, et al. Streptococcus pneumoniae in the heart subvert the host response through biofilm-mediated resident macrophage killing. PLoS Pathog. 2017 Aug 25;13(8):e1006582.

3: Reyes LF, et al. Severe Pneumococcal Pneumonia Causes Acute Cardiac Toxicity and Subsequent Cardiac Remodeling. Am J Respir Crit Care Med. 2017 Sep 1;196(5):609-620.

4: González-Juarbe N, et al. Pore-forming toxin-mediated ion dysregulation leads to death receptor-independent necroptosis of lung epithelial cells during bacterial pneumonia. Cell Death Differ. 2017 May;24(5):917-928.

REQUIREMENTS:

• PhD and/or MD/DDS and have training in microbiology or immunology
• Experience in microbial genomics, bacterial virulence, biofilms, cell culture, mouse work, microscopy, and innate immunology
• Candidates with experience in molecular genetics and/or bioinformatics will receive special consideration
• A strong publication record and excellent written and verbal communication skills
• Ambition to reach the next career level with a team player philosophy
• Ability to collaborate on multidisciplinary research projects

RESPONSIBILITIES:

• Conduct rigorous and original science
• Independently design, perform, and interpret experiments
• Write and publish high-quality peer-reviewed research
• Participate in grant writing
• Supervise and train undergraduate or graduate trainees and/or technicians

SALARY AND BENEFITS:

Salary and fringe benefits as per UAB and NIH guidelines.

HOW TO APPLY:

Interested candidates should apply through the ScienceCareers site. Please submit a single PDF file that includes a cover letter summarizing research accomplishments and career goals (1-2 pages), up-to-date curriculum vitae, a list of three references, and three relevant publications. Only candidates selected for an interview will be contacted.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.