Scientist, Oncology Research

Cambridge, MA
July 05 2019
Organization Type
Scientist, Oncology Research

The Role:

Moderna Oncology is seeking a talented, experienced, and motivated Principal Research Associate to join our oncology translational research team focused on intratumoral mRNA-based immunotherapies. The successful candidate will share our commitment to understanding the biological principles that drive response to our therapies. You will contribute to the development of assays to measure responses to our cancer immunotherapies, and will interrogate and report data derived from patient samples obtained from Moderna clinical trials. You should be both a great team member and have a demonstrable record of independent research accomplishments.

Here's What You'll Do:
  • Interpret and analyze clinical biomarker assay readouts, particularly from tumor tissue-based multiplexed quantitative immunofluorescence and immunohistochemistry assays
  • Contribute analyses to high quality study reports under ambitious timelines
  • Facilitate development and validation of fit-for-purpose biomarker assays, especially to perform immunophenotyping for use in clinical studies
  • Work with contract research organizations, interface with pathologists, and coordinate activities and timelines with clinical development teams to ensure execution of biomarker capabilities to support clinical studies
  • Routinely present work progress to project teams; provide scientific and technical support for multidisciplinary project teams
  • Maintain expertise in the field of immuno-oncology as it pertains to biomarker discovery and patient outcomes

Here's What You'll Bring to the Table:
  • PhD with 2+ years relevant experience
  • Background in oncology and immunology
  • Must have significant experience (2+ years) with immunohistochemistry/ immunofluorescence assay development, and quantitative and qualitative image analysis methods, particularly from tumor specimens
  • Broad experience in other cellular and molecular biology principals and techniques including ELISAs, MSD assays, Luminex, Westerns; gene expression by qPCR, NanoString, NGS; cell culture and cell transduction
  • Experienced with standard programs for data analysis and visualization
  • Attention to detail, scientific versatility, flexibility, results oriented, effective communication skills
  • Experience with assay development and validation under CAP/ CLIA and/or GLP standards a plus
  • C andidate will embrace our core values. You will be curious in exploring new paths for biomarker discovery, bold in proposing creative experimental designs and ideas. You will work collaboratively with multifunctional teams and will be relentless in pursuing successful outcomes.

Here's What We'll Bring to the Table:
  • Daily on-site catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Adoption assistance and discounts to local childcare centers, as well as access to
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays

Why Join Moderna Therapeutics

At Moderna, we believe messenger RNA, or mRNA, is the "software of life." Every cell in the body uses mRNA to provide real-time instructions to make the proteins necessary to drive all aspects of biology, including in human health and disease. Given its essential role, we believe mRNA could be used to create a new category of medicines with significant potential to improve the lives of patients.

Headquartered in Cambridge, Mass., Moderna currently has strategic alliances for development programs with AstraZeneca, Plc. and Merck, Inc., as well as the Defense Advanced Research Projects Agency (DARPA), an agency of the U.S. Department of Defense; and the Biomedical Advanced Research and Development Authority (BARDA), a division of the Office of the Assistant Secretary for Preparedness and Response (ASPR) within the U.S. Department of Health and Human Services (HHS). Moderna has been ranked in the top ten of Science's list of top biopharma industry employers for the past four years. To learn more, visit .

Our Mission:
Deliver on the promise of mRNA science to create a new generation of transformative medicines for patients.


Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

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