Post-Doctoral Research Fellow, Cancer Biology and Tumor Metastasis
Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch’s pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation’s first cancer prevention research program, as well as the clinical coordinating center of the Women’s Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
Two postdoctoral research positions are available in the laboratory of Dr. Kevin Cheung at the Fred Hutchinson Cancer Research Center. The Cheung lab works at the interface between cancer cell biology and translational research (Cell 2013; PNAS 2016; Science 2016). Our lab is specifically interested in circulating tumor cell clusters – clumps of cancer cells with significantly increased metastatic potential – and gaining experimental insight into their origins, attributes, and vulnerabilities.
Find out more about the work of the Cheung lab at: https://www.fredhutch.org/en/labs/profiles/cheung-kevin.html
Our research is generously supported by a DOD Era of Hope Scholar Award, the V Foundation, the Susan G. Komen Foundation, and the Burroughs Wellcome Fund. We are seeking highly motivated postdoc candidates interested in one of the following two research areas:
- Single cell seq and organoid biology - We are investigating the cellular composition of circulating tumor cell clusters and the different tumor and stromal interactions occurring within clusters. We are using single cell profiling, organoids, and murine models to screen these interactions and their roles during metastasis.
- Genome-scale library screening – We are dissecting the genetic programs controlling metastasis of tumor cell clusters and how these programs differ from single cell metastasis. Current projects involve CRISPR and drug library screens to identify genes and pathways that are essential for cluster-based metastasis.
- Responsibilities We are looking for candidates who are great communicators that value teamwork and can thrive in a fast paced environment. The ideal candidate will lead one of several core projects in our laboratory.
- A recent PhD or MD degree
- At least two first author publications are required
- Experience with organoids, library screening, and murine models is required
- Able to work both independently and as part of a laboratory team
Pay, Benefits, & Work Schedule: Full time position, Salary DOE + excellent benefits.
Please apply with a CV, three professional references, and a motivation letter for why you are specifically interested in this job opportunity.
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