Research Associate - Biochemical Information & Annotation Specialist (Biocurator)

Piscataway, New Jersey
Commensurate With Experience
March 08 2019
Position Type
Full Time
Organization Type

The RCSB Protein Data Bank (RCSB PDB, is a publicly accessible information portal for researchers and students interested in structural biology. At its center is the PDB Core Archive – the single global repository for the 3-dimensional structure data of biological macromolecules. These structures hold significant promise for the pharmaceutical and biotechnology industries in the search for new drugs and in efforts to understand human disease.

The primary mission of the RCSB PDB is to provide accurate, well-annotated data in the most timely and efficient way to facilitate new discoveries and scientific advances. The RCSB PDB processes, stores, and disseminates these important data, and develops the software tools needed to assist users in depositing (in collaboration with worldwide PDB partners) and accessing structural information.

The RCSB PDB at Rutgers University in Piscataway, NJ has an opening for a Biochemical Information & Annotation Specialist (Biocurator) to curate, validate, and standardize macromolecular structures for distribution in the PDB Core Archive. The Biocurator communicates daily with members of the deposition community, and annotates, releases, and updates entries in the PDB Core Archive. This position offers the opportunity to participate in exciting projects with significant impact on the scientific community.


Key Duties and Responsibilities
• Accurately biocurate and release new structures in a timely manner
• Regularly update and maintain existing structures in the PDB archive
• Provide excellent customer service to Data Depositors

Minimum Education and Experience

PhD in biological chemistry is required in order to validate chemical identity of small molecules, cross-check biological sequences with external sequence databases, and perform geometrical validation.

Experience in linux computer systems is preferred.

Required Knowledge, Skills, and Abilities

A background in cryo-electron microscopy (3DEM) or small molecule crystallography or macromolecular crystallography is a strong advantage to curate and validate structures determined by 3DEM or crystallography experimental methods.

Experience with metalloprotein, small molecules, and biological databases is preferred.

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