Programme Leader Track: Epigenetics

University of Cambridge
Cambridge, Cambridgeshire (GB)
£40,792 - £58,089
February 21 2019
Position Type
Full Time
Organization Type

Programme Leader Track: Epigenetics

The MRC Toxicology Unit in the University of Cambridge is seeking to appoint a Programme Leader Track at the grade of Senior Research Associate within the area of epigenetics.  The successful candidate will lead a small research team and be free to pursue their own research agenda within the theme of gene-environment interactions following toxic exposure.

We are particularly interested in those with a strong research record in this area for example, research directed towards determining how the DNA or RNA epigenome changes following exposure to pharmaceuticals/environmental agents. Proposed future studies should be directed at obtaining mechanistic information about the mode of action and physiological consequence of these epigenetic changes.

The appointment will be made at Programme Leader Track/Senior Research Associate level and will provide you with the opportunity to develop a full range of skills necessary to progress your research programme.  It is expected that within 5-6 years you will prove yourself fully able to be an internationally competitive group leader and equally merit promotion to Programme Leader/Principle Research Associate within the same time frame. Duties will include developing research objectives, projects and proposals for the delivery of your own research programme; leading a small team of researchers and PhD students; managing research budgets and resources; developing collaborations; identifying and securing funding; disseminating research findings in peer-reviewed literature and at international conferences.

The successful candidate will have made significant contributions to the subject area with important research papers in high quality journals; a PhD in a related discipline; relevant postdoctoral experience including leading others and outstanding potential for independent research. A background in toxicology is desirable but not essential.

The MRC Toxicology Unit is a leading international research institute within the School of Biological Sciences. The Unit delivers high impact mechanistic toxicology research, pursuing hypothesis-driven toxicological questions with a particular focus on the study of the causal links between exposure to endogenous and exogenous toxicants, molecular initiating events and adverse outcome pathways.  The Unit's overall aims are to carry out pioneering research which leads to improved health and to train and mentor the next generation of toxicologists. 

The research environment provides state-of-the-art research facilities including microscopy, Cryo-EM, flow cytometry; proteomics; bioinformatics and imaging.  In addition, excellent opportunities exist for collaborative interactions within a vibrant community at the University of Cambridge.

To apply for this position please provide your CV and a research proposal outlining the research questions you would like to address and why these are important to the study and advancement of toxicology, including the approaches you will take and resources required.

Interviews are expected to take place on 30th May 2019. The selection process will include a research presentation and panel interview.

We offer a generous support package, including intramural MRC funding, core-funded posts and PhD studentships. 

This is an open-ended position funded by the Medical Research Council. 

Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check and a security check.

To apply online for this vacancy and to view further information about the role, please visit:

Closing date: 08 April 2019

Informal enquiries are welcomed and should be directed to:

Professor Anne Willis

If you have any queries regarding the application process please contact Rebecca Heatherley

Please quote reference PU18201 on your application and in any correspondence about this vacancy.

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