Research Fellow-Microbiome Systems

Mayo Clinic
Rochester, Minnesota (US)
February 07 2019
Position Type
Full Time
Organization Type
Job Type
PhD Fellowship

The Microbiome Systems Medicine Group at Mayo Clinic (Rochester, MN, USA), led by Dr. Jaeyun Sung, invites applications for postdoctoral positions in systems approaches to ’omics data analysis and personalized medicine. This position has been created, in part, to increase our computational capacity to systematically analyze, integrate, and model the tremendous amount of longitudinal, multi-omics data currently being generated at Mayo Clinic. These data sources include microbiomes, genomes, proteomes, metabolomes, and clinical and physiological surveys. Our overall aim with these data is to further understand the complex interactions between commensal gut microbial organisms and various aspects of human health, particularly the immune system and metabolism. Current research fields include: 1) omics data-mining for clinical biomarker discovery; 2) metabolomics and exposomics; 3) multi-omic disease network analysis; 4) gut microbiome ecological dynamics; 5) microbial role in gut-liver axis; and 6) gut microbiome and auto-immune disease. Additional information can be found at:

Fellows will be mentored by Dr. Jaeyun Sung and other faculty investigators of the Microbiome Program in the Center for Individualized Medicine at the Mayo Clinic. The Center is a vibrant, well-funded environment, with strong mentoring and training opportunities for individual career development. In addition, the candidate will have access to a wealth of resources including high-quality clinical data, a state-of-the-art high-performance computing facility, and the latest sequencing platforms.

This is a computational position. The applicant must be strongly familiar with programming languages commonly used in data science (R, Python, and/or Matlab), and with standard bioinformatics tools for processing and analyzing ’omics datasets. The applicant should have a Ph.D. in one of the following fields: computational biology, biostatistics, bioinformatics, biophysics, applied math, or bio-/chemical-engineering. Ph.D. candidates with soon anticipated graduation are also encouraged to apply. Excellent written and verbal communication skills, strong ability to independently and creatively solve research problems, while working effectively with the principal investigator and lab colleagues, is required. Prior experience working with omics data analysis (WGS metagenomics, RNA-seq and scRNA-seq, MS metabolomics, immune CyTOF), computational microbiology or immunology, as demonstrated through past research accomplishments, would be ideal.

If you are interested in joining, please email Dr. Jaeyun Sung ( your CV, contact information of three individuals who can provide strong reference letters, PDFs of 3 of your representative publications, and a 1-page personal statement describing: your general research interests, previous experience, career goals, and specific research direction you’d like to pursue in our group.

Mayo Clinic is located in the heart of downtown Rochester, Minnesota, a vibrant, friendly city that provides a highly livable environment for more than 34,000 Mayo staff and students. The city is consistently ranked among the best places to live in the United States because of its affordable cost of living, healthy lifestyle, excellent school systems and exceptionally high quality of life.

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