Postdoctoral fellowship positions in cancer biology at UCSF

Location
San Francisco, California
Salary
Commensurate with experience and accomplishments; starting at NIH pay scale + benefits
Posted
January 16 2019
Position Type
Full Time
Organization Type
Academia

Postdoctoral fellowship positions in cancer biology at UCSF

The Solomon Laboratory at UCSF (https://solomonlab.ucsf.edu) is seeking highly motivated postdoctoral research fellows to lead NIH-funded studies examining the role of the cohesin complex in cancer pathogenesis and other translational research projects aimed at deciphering the molecular mechanisms by which novel genetic discoveries in human tumors drive oncogenesis.  Specific projects focus on the mechanisms by which the cohesin subunit STAG2 controls replication fork procession and DNA repair, as well as studying the mechanisms by which STAG2 controls mammalian development using a newly developed conditional knockout mouse.  Another ongoing study is examining the role of the TRAF7 gene in the pathogenesis of mesotheliomas and meningiomas, tumors in which mutations in this ubiquitin ligase gene are frequent.  We are fundamentally interested in understanding why certain oncogenes and tumor suppressor genes are altered in specific tumor types to drive oncogenesis (for example, why STAG2 mutations are common in glioblastoma, urothelial carcinoma, and Ewing sarcoma but not renal cell carcinoma or osteosarcoma).  Our prior studies have been featured in Science, Nature Genetics, Nature Communications, Cancer Research, Journal of Cell Biology, Modern Pathology, Acta Neuropathologica, and other high-impact journals.

Enthusiastic and self-motivated candidates are encouraged to apply. The successful candidate(s) will have a range of opportunities to pursue translational patient-oriented cancer research, with structured mentoring support and opportunities for travel and presentation at national meetings.  Additional professional development opportunities are available through our affiliation with the UCSF Helen Diller Family Comprehensive Cancer Center (http://cancer.ucsf.edu/), the UCSF Department of Pathology (http://pathology.ucsf.edu/), the UCSF Clinical Cancer Genomics Laboratory (https://gmi.ucsf.edu/), and the UCSF Biomedical Sciences Graduate Program (https://bms.ucsf.edu/).

Requirements:

Candidates should possess a Ph.D. and/or M.D.  A background in cell biology or cancer biology research is preferred.  Experience with techniques including cell culture, flow cytometry, DNA cloning, Western blotting, immunoprecipitation, CRISPR gene editing, and expression microarray or RNA-seq analysis are desirable. Excellent communication and writing skills are essential.  Fluency in English required.  Applicants should be US citizens, permanent residents, or must currently hold a valid US work visa.

How to apply:

Interested candidates should email a cover letter, CV, and the names of 3 references to Dr. David Solomon, Assistant Professor, Department of Pathology, UCSF to david.solomon@ucsf.edu.  Please use subject heading "Postdoctoral Fellow position".

The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.

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