Postdoctoral fellow in T-cell immunology and cancer immunotherapy

Location
Montréal, Quebec (CA)
Salary
Postdoctoral fellow in cancer immunotherapy
Posted
November 15 2018
Position Type
Full Time
Organization Type
Academia

We have an opening for a postdoctoral fellow to join our immunology group headed by Dr. Christopher Rudd at the CR-Hôpital Maisonneuve Rosemont, a research institute affiliated with the Université de Montréal. The project will involve investigating T-cell signaling pathways that influence T-cell responses to cancer and infection. We are a leading international group that has defined many of the key intracellular events that regulate T-cell activation such as CD4/CD8-p56lckand co-receptor signaling. As well,  CD28 motifs discovered in the Rudd lab are used in the generation of chimeric antigen receptor (CAR) therapy.  Present projects include an analysis of the function of different co-receptors such as CD28, PD-1, CTLA-4 in the modulation of T-cell function and anti-tumor immunity.  A special focus is on the nature of T-cell signaling events that lead to improved cancer immunotherapy. We are part of a collaborative, interdisciplinary research center with a strong group of researchers with expertise in T cell biology and cancer. The projects involve a variety of cellular and molecular biology techniques as well as mouse models of cancer together with multi-photon microscopy to study mouse and human disease. Papers of interest include Liu et al., 2015 Molecular Cell 59, 840-849; Taylor et al2016 Immunity, 44:274-86; Krueger J and Rudd CE.(2017) Immunity 46, 529-531; Raab et al., Nat Commun. 2017 8:16001; Taylor et al., 2018 Cancer Research, 78(3):706-717].

Please send a curriculum vitae with a list of publications, a statement of research interests and the names of three references to:  Dr. Christopher Rudd (christopher.e.rudd@umontreal.ca) or administrative assistant, Nathalie Ross (nathalie.ross.cemtl@ssss.gouv.qc.ca)

 

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