Director of Biological Discovery
The Institute for Protein Innovation (IPI) seeks a Director of Biological Discovery to lead our target selection and biological validation programs. The IPI, a 501(c)(3) non-profit organization embedded within the Harvard Medical School Longwood Area, has established itself as a premier center for protein science and has implemented state-of-the-art automation for high-throughput antibody discovery. The long-term mission of the IPI is the discovery of antibodies targeting all secreted and cell surface proteins from human and mouse to serve as both tool compounds and leads for potential new therapeutics. To maximize biological and therapeutic impact, the IPI has adopted a strategy that includes the targeting of functionally related groups of protein families, such as those that participate in stem cell signaling, specifying neuronal synapses, or regulating immune responses. The Director of Biological Discovery will take a lead role in target selection, including identifying areas of biological importance, as well as detailed antigen design to maximize production of antibodies that modulate biological processes. Exceptional communication and organizational skills are critical, as the Director will be responsible for the organization and oversight of community-based workshops in which IPI-generated antibodies are distributed to community members for expert validation, evaluation in cell-based and animal-based models, and dissemination in publications. This position offers a unique opportunity to straddle academics and therapeutics, with enormous prospects for discovery and intellectual property generation. Candidates should hold a PhD (or equivalent degree) and have at least three years of postdoctoral experience, with demonstrated expertise in structural immunology, structural neurobiology, sequence-based assessment of biological function, or a related field. The Director of Biological Discovery has the opportunity to receive a part-time academic appointment as Assistant Professor at Boston Children’s Hospital and Harvard Medical School. This joint appointment affords the opportunity to participate in teaching activities, with enhanced opportunities for intimate collaborations with the exceptional scientific community within and surrounding Harvard Medical School.
Interested candidates should send a CV and a brief statement of future research interests as a single PDF to firstname.lastname@example.org, and arrange for three letters of reference be sent to the same address.