Research Scientist - Computational

November 06 2018
Life Sciences
Position Type
Full Time
Organization Type
Job Type
It is an exciting time to be a part of Lilly Biotechnology Center in San Diego. We are growing our capabilities in Computational biology and need talented and high-energy scientists to join our dynamic team. Are you experienced in applying molecular modeling and simulation based approaches to further optimize molecular recognition, efficient heavy-light chain pairings, antibody develop-ability properties, safety and PK/PD in a synergistic manner? Have you had the desire to use your strong computational skills to tackle protein property and characterization challenges from a structural perspective? Lilly is looking for a highly motivated bioinformatics scientist to join our Biologics group to develop and apply computational algorithms enabling development of computational workflows to identify and optimize Fabs, scFv and multispecifics. Your role will involve collaborating with biotechnology scientists (protein engineers, antibody discovery, protein biosciences, etc) and applying ground breaking computational approaches to discover and build the best therapeutic proteins faster. Your contributions will include (1) applying machine learning and predictive modeling to assist in biologic drug discovery, (2) developing next generation databases to integrate heterogeneous workflow data and implementing data mining applications to meet specific project needs, and (3) evaluating novel computational algorithms and software applications.
Are you a phenomenal teammate and a focused individual with a strong work ethic and attention to detail? Do you have a strong interest in applying your knowledge, tools and methods for biologics engineering and drug discovery?This could be the career move for you.

Company Overview
At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our 39,000 employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.

Basic Qualifications
  • PhD degree in computational biology, bioinformatics or related discipline.

Additional Skills/Preferences
  • Scientific proficiency, creativity, ability to collaborate effectively with others, and independent thought processes.
  • Must be capable of working on problems of diverse scope in which analysis of data requires a detailed evaluation of possible factors.
  • Strong programming skills in one of the high level programming languages (Python, Java, C/C++) and proficient in a scripting language (e.g. R, Perl, SQL).
  • Excellent communication skills and a broad knowledge of the technologies in use. Able to distill and relay complex technical/scientific concepts to a variety of members within the organization.
  • Expected to be or become familiar with the background knowledge and technology required to address the goals of a discovery program or research task.
  • Comfortable working with high performance or cloud computing environment and relational databases.
  • An ability to train and evaluate machine learning models, such as linear and logistic regression, SVMs, Random Forests, neural networking and Gradient Boosting etc.

Additional Information
  • Lilly is an EEO/Affirmative Action Employer and does not discriminate on the basis of age, race, color, religion, gender, sexual orientation, gender identity, gender expression, national origin, protected veteran status, disability or any other legally protected status.
  • Lilly earns consistent and wide recognition for creating an exceptional work environment:
    • Business Week magazine 50 Best Places To Launch A Career™
    • FORTUNE America's Most Admired Companies™
    • FORTUNE 50 Best Companies for Minorities™
    • Working Mother 100 Best Companies for Working Mothers™
    • Industry Week magazine 100 Best-Managed Companies™
    • Science magazine Best Companies for Scientists™

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