Postdoctoral Position - RNA Dynamics Lab

Employer
Florida Atlantic University - FAU
Location
Jupiter, Florida
Salary
DOE
Posted
November 02 2018
Position Type
Full Time
Organization Type
Academia

Florida Atlantic University is seeking two postdoctoral positions in the RNA Dynamics Lab, Jupiter, FL.

 

With over 30,000 students from all 50 states and over 180 countries, 21 intercollegiate teams, 180 plus degree programs, and an administration that thrives on discovery and excellence, FAU is pushing the boundaries of higher education. Florida Atlantic's faculty and staff are trailblazers and innovators with a passion for finding creative solutions while advancing science, art, and technology in all disciplines. Our work environment is a hub of cultures from across the nation and the world, making FAU a place where collaboration flourishes.

 

Dr. Ilyas Yildirim in the Department of Chemistry and Biochemistry, is recruiting motivated and qualified postdoctoral scholars to investigate properties of biologically significant RNA molecules. Our goal is to create physics-based computational methods and models for RNA that has therapeutic applications.

 

The research group performs studies on RNA force fields, utilizes molecular dynamics simulations and free energy landscape prediction methods to calculate the structural and thermodynamic properties of exotic RNA systems, and develops new methods to design next-generation drugs targeting RNA molecules. We are also interested in RNA folding, and 3D structure prediction of challenging RNA loops.

 

Systems studied include RNA repeat expansions causing genetic diseases (Myotonic Dystrophy Type 1 and 2, Huntington 's disease, and Fragile X-Syndrome), biologically significant RNA internal loops, RNA G-quadruplex, and Ago2-microRNA complex. Research involves active collaboration with Scripps Research Institute Florida, University of Cambridge, and several other research groups in US and Europe. We use the FAU and Scripps High Performance Computing clusters, which have both CPU and GPU clusters, to perform the calculations.

 

For additional information about the RNA Dynamics Lab, visit our webpage at http://cosweb1.fau.edu/~iyildirim.

 

Minimum Qualification:

 

PhD from an accredited intuition in a related field (e.g., theoretical and/or computational chemistry/physics) by the time of appointment required.

Strong written and verbal communication skills are required.

Experience using molecular dynamics simulations, quantum mechanical calculations required.

Must be proficient in scientific programming.

Experience with methods development and coding in a molecular simulation package preferred.

Gaussian and/or GAMESS-US ab initio software and AMBER MD package knowledge preferred.

Experience with free energy calculation methods (MMPBSA/GBSA, Thermodynamic Integration approach, Umbrella Sampling, Discrete Path Sampling, or any other energy landscape prediction method) preferred.

 

All applicants must apply electronically to the currently posted position Postdoctoral Fellow on the Office of Human Resources' job website (https://fau.edu/jobs) by completing the required online employment application and submitting the related documents. When completing the online application, please upload the following: a cover letter, curriculum vitae, a list of three references with contact information including mailing address, phone number and e-mail address, and copies of official transcripts scanned into an electronic format.

 

A background check will be required for the candidate selected for this position. This position is subject to funding.

 

For more information and to apply, visit www.fau.edu/jobs and go to Apply Now REQ04698.

 

Florida Atlantic University is an equal opportunity/affirmative action/equal access institution and all qualified applicants will receive consideration without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability status, protected veterans status or other protected status. Individuals with disabilities requiring accommodation, please call 561-297-3057. 711.

 

FAU is committed to the principles of engaged teaching, research and service. All persons aspiring to achieve excellence in the practice of these principles are encouraged to apply.



Apply Here: http://www.Click2Apply.net/btqnxtw3wjr7fdph

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