Postdoctoral Associate Physiology and Biophysics

Stony Brook University
Stony Brook, New York
October 22 2018
Position Type
Full Time
Organization Type

The Bowen Lab is working to reconstitute the postsynaptic density from excitatory neurons in vitro to understand the role of scaffold proteins in the assembly of membrane-associated signaling complexes. We use fluorescence microscopy to study the structure and function of individual protein molecules within this reconstituted system. The Bowen lab has extensive experience in recombinant protein production in both prokaryotic and eukaryotic cells and is equipped with systems for both prism-based and through-objective TIRF microscopy using six-color illumination. We are seeking a highly motivated individual with imaging experience and an interest in protein structure and protein interactions. Interested applicants should apply on line at In key word search insert 1802601.

Required Qualifications

PhD in the Physical or Biological Sciences

One or more First-Authored Publications demonstrating relevant experience.

Ability to work autonomously and collaborate with a diverse team of scientists.

Fluency in English and strong written and spoken communication skills.

Hands-on Experience in one or more of the following:

  1. Collection of Quantitative Fluorescence Microscopy data
  2. Kinetic analysis/modeling of biological phenomena
  3. Scientific programming and image analysis in MATLAB
  4. Construction and maintenance of microscopy instrumentation

Preferred Qualifications

Hands on experience in one or more of the following:

  1. Single Molecule and/or Super-Resolved Microscopy
  2. Live cell imaging
  3. Single Particle Tracking
  4. Familiarity with Metamorph, LabVIEW, Igor

Duties include:

The Postdoctoral Associate will assist the Principal Investigator in the department of Physiology & Biophysics to develop, execute, and publish research projects related to clustering of glutamate receptors and scaffold-mediated protein interactions.

Perform hands-on data collection involving imaging of fluorescently-labeled recombinant proteins in lipid bilayers.

Analyze fluorescence microscopy data to extract information about protein structure and function.

Spoken and written presentation of results in lab meetings, conferences and peer-reviewed publications.

What we offer:

A supportive environment with the opportunity for intellectual and professional growth

Opportunities to gain experience in cutting-edge biophysical and imaging techniques.

Fully funded position (renewed annually for up to 4 years)

Stony Brook University is an internationally-recognized public research institution and a member of the Association of American Universities. Located on the beautiful and scenic North Shore of Long Island, Stony Brook is situated 60 miles from New York City and close to the farms and wine country of the North Fork.


Equal Opportunity Employer, females, minorities, disabled, veterans.

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