Research positions for identification and CRISPR/Cas9 gene correction of primary immunodeficiencies

Department of Biomedicine, Aarhus University
Aarhus C, Aarhus (DK)
October 12 2018
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Department of Biomedicine, Aarhus University and Departments of Infectious Diseases and Clinical Immunology, Aarhus University Hospital

Four research positions are available at Aarhus University, Denmark and Aarhus University Hospital, Denmark. All positions are for appointments for three years with an intended starting date of January 1st, 2019.

The positions are associated with a larger translational research program on CRISPR/Cas9-mediated gene editing of hematopoietic stem cells for patients with primary immunodeficiency diseases.

A. One post doc position is available in the laboratory of Trine Mogensen on a project identifying novel immunodeficiencies in patients using whole exome sequencing, bioinformatics, and functional immunological assays.
B. Two post doc positions are available in the laboratories of Jacob Giehm Mikkelsen and Rasmus O. Bak, respectively, on projects centered on the development of CRISPR/Cas9 reagents for hematopoietic stem cell gene correction and functional genetic and immunological validation of developed reagents in vitro and in vivo.
C. One clinical specialist position is available in the laboratory of Bjarne K. Møller on hematopoietic stem cell expansion and establishing Good Manufacturing Practice (GMP)-compliant procedures for cell manufacturing and translation of experimental methods into clinical practice.

All applicants are required to have published at least one first-author publication of high quality in an international, peer-reviewed journal. Furthermore, solid background knowledge and experimental experience within genetics, molecular and cell biology are required. Depending on the position, experience within genome editing, immunology of primary immunodeficiencies, mesenchymal and hematopoietic stem cell biology, or GMP is highly valued, as well as skills in AAV vectorology, flow cytometry, animal handling, and bioinformatics. Finally, the successful candidates are expected to have ambitions and skills to develop the projects to the highest international level, and to be engaged in activities across the consortium and in supervision of junior students (PhD students, medical students, and Masters students).

Please apply for positions A, B1, and B2 using the link at the bottom. To apply for position C, please apply using the application system at Aarhus University Hospital, click here.

Professor MSO Trine Mogensen, MD PhD DMSc, e-mail: (position A)
Professor MSO Jacob Giehm Mikkelsen, PhD, e-mail: (position B1)
Associate Professor Rasmus O. Bak, PhD, e-mail: (position B2)
Associate Professor, Bjarne K. Møller, MD, e-mail: (position C)


Required qualifications
Appointment as a postdoc requires academic qualifications at PhD level.

Formalities and references

The application must be accompanied by a curriculum vitae, complete list of publications, letters of recommendations, information on teaching qualifications, and an account on the specific position applied for. Template for applicant - postdoc must be completed and uploaded under Other information to consider. A maximum of five of the publications of greatest relevance to the job must be submitted.

Further information on the application and supplementary materials may be found in the facultys Guidelines for applicants for academic positions and Aarhus Universitys Guidelines on the use of teaching portfolios.

The assessment committee may decide to include non-submitted material in its assessment. In such cases, the applicant will be informed and obliged to submit material, unless the application is withdrawn.

Applications submitted through channels other than the online application form below or applications which are not received by the application deadline will not be considered.

All interested candidates are encouraged to apply, regardless of their personal background.

All applications must be made online and received by 15 November 2018.

Please apply online here

International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.

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