A postdoctoral position is available immediately in Dr. Radwanski’s laboratory in the Bob and Corrine Frick Center for Heart Failure and Arrhythmia at the Ohio State University. Our lab is investigating the role of sodium-calcium nanodmains in cardiac arrhythmogenesis, with the particular focus on the involvement of non-cardiac-type sodium channels in the triggering process. We use an array of techniques and models including optical mapping of ex vivo hearts, conventional (patch clamp) and fluorescence-coupled electrophysiology (patch clamp in tandem with rapid confocal calcium imaging) and scanning ion conductance microscopy-guided single-channel recordings (aka smart-patch). This position is for an applicant who will use cellular and electrophysiological techniques to measure the direct and indirect effects of various agents on voltage-gated sodium channels in cardiomyocytes and those expressed in heterologous systems. Successful candidates can be involved in multiple projects to enhance productivity and training objectives to develop novel skillsets commensurate with the applicant’s career goals.
Preferred expertise: Prior experience with cellular electrophysiology is preferred. Expertise in cell culture and molecular biological techniques is also of value. Postdoctoral fellows and PhD students in the final stages of their degree are encouraged to apply.
Appointment: The position is available from October 5, 2018. Applicants will be reviewed immediately and until the position is filled. Salary will be funded through recently awarded NIH grant funds and will be commensurate with qualifications and experience.