Postdoctoral Fellow | Signaling Mechanisms Underlying Circadian Clock Control

Location
California
Salary
Competitive
Posted
September 19 2018
Discipline
Life Sciences
Position Type
Full Time
Organization Type
Healthcare/Hospital
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

Requisition 14695

Postdoctoral Fellow | Signaling Mechanisms Underlying Circadian Clock Control

Position Summary and Key Responsibilities:

A Postdoctoral Fellow position is immediately available in the laboratory of Dr. Ke Ma, Associate Professor, at the Diabetes and Metabolism Research Institute within Beckman Research Institute of City of Hope, CA. The Ma lab applies state-of-the-art circadian biology, molecular and cellular biology approaches to diabetes and obesity research, and we have established a unique program in deciphering the signaling mechanisms underlying circadian clock control in metabolic tissue development, growth and functional capacity. We are looking for highly motivated postdoctoral fellows with strong enthusiasm for metabolic disease or stem cell research to discover novel signaling and epigenetic mechanisms mediating circadian clock functions in adipose depots and skeletal muscle. Ultimately, our goal is to unravel circadian etiologies underlying the current epidemics of metabolic diseases for targeted therapeutic interventions. Utilizing biochemical and molecular biology approaches combined with animal physiology in genetic mouse models, the specific research directions in Ma Lab will explore, 1) epigenetic networks mediating clock nutrient-sensing function in adipose tissue and skeletal muscle; 2) circadian clock regulation of stem cell behavior in skeletal muscle development, growth, and regeneration; and 3) novel roles of circadian regulators in cancer development and metabolism. The postdoctoral candidate should be self-motivated, with a proven track record of productivity and strong interest in metabolic disease or stem cell research. Expertise in biochemistry, molecular biology and animal metabolic studies is preferred, and technical skill in stem cell research and epigenetics is a plus. To apply, please provide your CV and a list of three references.

Minimum Education and Skills Required for Consideration:

  • PhD in Molecular, Cellular or Developmental Biology.
  • Proficiency with biochemical techniques, molecular biology skills and cell culture systems.
  • Experience with in vivo animal model research preferred.
  • Experience with stem cell research preferred.
  • Experience with epigenetics research a plus.
  • Highly motivated with strong interest in metabolic disease research.
  • Strong work ethic and ability to work effectively in a team.

For a list of lab publications, please see: https://www.ncbi.nlm.nih.gov/sites/myncbi/1nGzbI8hm7LQU/bibliography/53125498/public/?sort=date&direction=ascending

Link for applying to these positions:

https://chm.tbe.taleo.net/chm04/ats/careers/v2/viewRequisition?org=CITYOFHOPE&cws=40&rid=14695

PI Webpage at the Diabetes and Metabolism Research Institute at City of Hope:

https://www.cityofhope.org/ke-ma

For additional information, please contact PI directly: kema@coh.org

Ke Ma, MD, PhD

Associate Professor
Department of Diabetes Complications and Metabolism
Diabetes and Metabolism Research Institute
Beckman Research Institute, City of Hope

Duarte, CA, 91010

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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