Research Scientist, Synthetic Neurobiology

Location
Cambridge, Massachusetts (US)
Salary
TBD
Posted
August 22 2018
Position Type
Full Time
Organization Type
Academia

Job Description - Research Scientist, Neural Circuits of Larval Zebrafish

Synthetic Neurobiology research group develops cutting-edge methods for mapping and controlling neural activity in the brain. We are looking for a Research Scientist – Neural Circuits of Larval Zebrafish to develop new genetically encoded molecular technologies that enable the ability to optically record neural activity in the larval zebrafish brain at biologically relevant spatiotemporal resolutions.

Responsibilities

  • Conduct research on the design and development of technologies, as well as validation of the developed technologies, via molecular and cellular techniques using the larval zebrafish model;
  • Teach and deploy such technologies into collaborating labs;
  • Write proposals to secure further research funding;
  • Write and present research results;
  • Collaborate and help research group team members and other collaborating students and postdocs on zebrafish research; and
  • Assist with lab coordination.

 

Qualifications

REQUIRED:

  • PhD in Biotechnology, Biology, Neuroscience, or a related field;
  • At least three years of experience working in the larval zebrafish model;
  • Extensive expertise in microinjection for transient expression and creating transgenic lines for zebrafish brain imaging required;
  • Excellent interpersonal skills and collaborative skills;
  • Demonstrated superb analytical/problem solving/critical thinking skills and judgment;
  • Attention to detail, superb organizational, documentation, communication, and time management skills required;
  • Able to work independently and self-motivated, one who is able to work as part of a tightly-knit team; and
  • Demonstrated background and interest in neuroscience is required.

PREFERRED:

  • Software skills and in silico protein design experience.

Those who are interested should submit a resume and cover letter referencing job no. 16161 at http://careers.mit.edu; keyword is "Media Lab".

 

Job Description - Research Scientist, Molecular Connectomic Technology in Mouse Brain

Synthetic Neurobiology research group develops cutting-edge methods for mapping the wiring and molecular composition of the brain. We are looking for a Research Scientist – Molecular Connectomic Technology in Mouse Brain to develop new viral, nucleic acid, and protein-based technologies for labeling neurons in the mouse brain for connectomic mapping.

Responsibilities

  • Conduct research on the applying expansion microscopy to the visualization of mouse brain tissues;
  • Teach and deploy such technologies into collaborating labs;
  • Write proposals to secure further research funding;
  • Write and present research results;
  • Collaborate and help research group team members and other collaborating students and postdocs on mouse brain research; and
  • Assist with lab coordination.

Qualifications

  • PhD in Biological Engineering, Neuroscience, or a related field;
  • At least three years of experience working live mouse brain experiments;
  • Extensive expertise in molecular cloning, viral tool design and construction, and in vivo delivery of viral vectors (via intracranial injection or in utero electroporation) is required;
  • Experience in fluorescence microscopy, tissue processing, in situ hybridization and/or sequencing, DNA library construction, and DNA sequencing is also required;
  • Excellent interpersonal skills and collaborative skills;
  • Demonstrated superb analytical/problem solving/critical thinking skills and judgment;
  • Attention to detail, superb organizational, documentation, communication, and time management skills required;
  • Able to work independently and self-motivated, one who is able to work as part of a tightly-knit team;
  • Demonstrated background and interest in neural circuit mapping is required.

Those who are interested should submit a resume and cover letter referencing job no. 16159 at http://careers.mit.edu; keyword is "Media Lab".

 

Job Description - Research Scientist, Optimization and Application of Expansion Microscopy

Synthetic Neurobiology research group develops cutting-edge methods for methods for mapping the wiring and molecular composition of the brain. We are looking for a Research Scientist – optimization and application of expansion microscopy to help optimize and apply expansion microscopy, alone and in combination with novel in situ sequencing techniques, for the multimodal mapping of large numbers of biomolecules throughout diverse cells and tissues in healthy and disease states.

Responsibilities

  • Help design, validate, and optimize the expansion microscopy and in situ sequencing protocols and help apply the resulting tools to normal and diseased brain tissue, and a diversity of other tissue types such as cancers and help analyze the data;
  • Write proposals to secure further research funding;
  • Write and present research results;
  • Collaborate and help research group team members and other collaborating students and postdocs on molecular mapping research;
  • Assist with lab coordination.

Qualifications

REQUIRED:

  • PhD in Biological Engineering, Biology, Neuroscience, or a related field;
  • At least one year of working experience with tissue handling, microscopy, and image data analysis;
  • Extensive expertise in molecular cloning, optical microscopy, and software skills (e.g., MATLAB programming, Linux systems, shell scripting) is required;
  • Excellent interpersonal skills and collaborative skills;
  • Demonstrated superb analytical/problem solving/critical thinking skills and judgment;
  • Attention to detail, superb organizational, documentation, communication, and time management skills required;
  • Able to work independently and self-motivated, one who is able to work as part of a tightly-knit team;
  • Demonstrated background and interest in neuroscience is required.

PREFERRED:

  • Experience in next-gen DNA sequencing and data analysis;
  • Demonstrated background and interest in neuroscience and/or cancer research.

Those who are interested should submit a resume and cover letter referencing job no. 16162 at http://careers.mit.edu; keyword is "Media Lab".

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