Postdoctoral Position in Cancer Genomics and Precision Oncology

New York City, New York (US)
Full Time + Benefits
August 22 2018
Position Type
Full Time
Organization Type

Postdoctoral Position in Cancer Genomics and Precision Oncology


Company Overview

At Memorial Sloan Kettering (MSK), we’re not only changing the way we treat cancer, but also the way the world thinks about it. By working together and pushing forward with innovation and discovery, we’re driving excellence and improving outcomes.
For the 26th year, MSK has been named a top hospital for cancer by U.S. News & World Report. We’re treating cancer, one patient at a time. Join us and make a difference every day.

Job Description

The laboratory of Timothy Chan, MD, PhD is recruiting for a postdoctoral fellow in cancer genetics. We are a laboratory of 20 members, ranging from graduate students, technicians, postdocs, staff scientists and faculty investigators. We collaborate closely with the Immunogenomics and Precision Oncology Platform (IPOP), a newly established collaborative research program at MSK directed by Dr. Chan and other faculty in the lab.

This fellow position is focused on molecular genetics, mouse experimentation, and immune-oncology as applied to human cancer. We are seeking a highly motivated candidate with a background in molecular/cellular biology to work at the interface of cancer genetics, molecular biology, genomic analysis, and tumor immunology, with Dr. Timothy Chan.

The fellow will work on high impact projects focusing on cancer genetics, cancer therapies and functional genomics.  He or she will carry out analyses linking findings in the tumor genome to functional assays and/or the tumor immune microenvironment.

Potential projects include but are not limited to immunocompetent mouse models of cancer, analysis of multi-omic datasets of thousands of cancers treated with standard therapies and/or immunotherapy, investigation of tumor suppressor genes relevant to carcinogenesis, developing new immunocompetent mouse models of tumors, and immunologic interrogations of checkpoint blockade, combination therapies, and neoantigen screens in patient tumors and model systems.

The Chan Laboratory comprises a dynamic group working collaboratively across the spectrum of cancer research, from basic molecular genetics, tumor immunology, mouse modeling, to computational biology and bioinformatics.  Approaches utilized include sequencing of exomes, transcriptomes, and T cell repertoires, as well as neoantigen immunogenicity screens, molecular cloning, biochemistry, and mouse models.

Applicants should hold a top-tier PhD degree (cancer biology, molecular biology, molecular genetics, or similar field), and must have strong laboratory and analytical skills. The candidate will be expected to work both independently and collaboratively, and have weekly in-depth meetings and regular access to your faculty advisors. Significant experience in mouse experimentation (breeding, handling) and mouse genetics is preferred, as well as significant experience with cell culture and molecular genetics techniques (cloning, DNA plasmid techniques, and CRISPR/Cas9). Experience and background in immunology are preferred. Good communication, organizational skills, and recordkeeping are a must. You will be exposed to weekly high-level cancer research seminars and symposia at MSKCC, and you will also present your work at regular lab meetings and teach/mentor graduate students, technicians and other postdoctoral fellows.

Memorial Sloan Kettering Cancer Center is an equal opportunity employer with a strong commitment to enhancing the diversity of its faculty and staff.  Women and applicants from diverse racial, ethnic and cultural backgrounds are encouraged to apply.

Mailing Address

Dr. Timothy A. Chan
Human Oncology and Pathogenesis Program
Memorial Sloan Kettering Cancer Center
1275 York Ave, Box 20
New York, NY 10065


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