Postdoctoral Position on Gene Regulation, Computational Biology and Cancer Biology

Chapel Hill, North Carolina (US)
Around $8,000 in addition to covered medical insurance
July 24 2018
Health Sciences
Position Type
Full Time
Organization Type
Job Type

Postdoctoral Position on Gene Regulation, Computational Biology and Cancer Biology

The Lineberger Comprehensive Cancer Center  
Department of Biochemistry
University of North Carolina at Chapel Hill (UNC) School of Medicine

Job Description

Postdoctoral associate positions available for the highly motivated candidate with a freshly completed PHD training in biochemistry, molecular biology, or cancer biology to join the Lineberger Comprehensive Cancer Center (an NCI designated cancer center) and Department of Biochemistry, University of North Carolina at Chapel Hill (UNC) School of Medicine, USA.

Our lab (see webpage: emphasizes on mechanistic understanding of chromatin modification, gene regulation, stem cells and diseases, notably cancer. We have recently published our findings of various chromatin/gene-regulatory mechanisms, which include those related to DNA methylation and histone modifications, at the well-received journals Molecular Cell 2013, Blood 2015, Cell Reports 2015, Cancer Cell 2016, Nature 2018, Stem Cell Reports 2018 and Molecular Cell 2018 (in press).

With recent acquisitions of funds from NIH/NCI, American Cancer Society (ACS) and Leukemia & Lymphoma Society (LLS), we have relatively long-term postdoc position (~5 years) available for postdoctoral associate focusing on either experimental biology OR computational analysis of genomics datasets.

The on-going projects include (1) biochemical characterization of epigenetic factors/complexes that regulate gene expression in stem cells or cancer cells; (2) CRISPR/dCas9-based editing and screening of pathways crucial for cancer development; (3) knockout and knock-in mouse models with deficiency in histone /DNA methylation regulation in context of development and tumorigenesis, with a special focus on hematopoietic disease; (4) epigenomic and transcriptome analyses (ChIP-Seq and RNA-Seq) of normal versus cancer cells to understand 3D chromatin structure and to delineate pathways essential for tumor growth.

Applicants should be self-motivated with a track record of publication in the above area, have laboratory and analytical skills, and be a critical thinker. Application shall include CV, a cover letter (with summary of research experiences and future interests, and expected availability date), reprints of publications, and contact information of three references. Please visit  to apply for this position.

The starting annual salary for this postdoc position is around $48,000 in addition to covered medical insurance.

The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.