Postdoctoral Position in Experimental Neuropathology of Diseases Caused by Protein Misfolding

Location
Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA
Salary
Commensurate with experience and track record
Posted
June 25 2018
Position Type
Full Time
Organization Type
Academia

Postdoctoral Position in Experimental Neuropathology of Diseases Caused by Protein Misfolding

The laboratory of Dr. Jiri Safar in the Department of Pathology at the Case Western Reserve University School of Medicine (CWRU) has a postdoctoral position available under the NIH R01 5-year grant in collaboration with the Department of Physiology and Biophysics at CWRU. The laboratory utilizes cutting edge biophysical and genetic tools including transgenic mice, to study the mechanism of formation of prions and prion-like amyloids, their evolution and selection in the pathogenesis of Alzheimer’s and prion diseases. The Safar’s team has recently synthesized the first artificial human prion [Kim et al., Nature Communications (2018) 9:2166] and ongoing projects are focusing on defining the mechanisms of prion formation and replication in different human prion strains. The project would be ideally suited to a postdoctoral fellow withPh.D. or M.D., and experiencein mass spectroscopy-based proteomics of protein misfolding diseases, and biochemistry of prions and prion-like proteins. 

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