Postdoctoral position on Drosophila tumor models
A postdoctoral position is available at the Wu-Min Deng lab in FSU. Supported by grants from NIH, NSF and Florida Department of Health, the Deng lab is interested in how intercellular communications affect normal development and how disruption of such communications leads to abnormalities such as tumorigenesis in the Drosophila model system. The major research topics include: (1) Notch signaling in development in tumorigenesis; (2) Cell competition and compensatory growth; and (3) The effects of tissue microenvironment on tumor initiation and progression.
Candidates for the postdoctoral position should have a Ph.D. degree, and a high degree of interest and motivation toward applying genetic, genomic, biochemical and molecular methods to investigate basic biological questions in development and Drosophila tumor models. Prior experience in Drosophila and/or genomics will be helpful.
For those who are interested in the position, please email email@example.com.
Professor Wu-Min Deng
Department of Biological Science
Florida State University
Tallahassee, FL 32306-4295
Tamori, Y., Bialucha, C. U., Tian, A.-G., Kajita, M., Huang, Y.-C., Norman, M., Harrison, N., Poulton, J., Ivanovitch, K., Disch, L., Liu, T., Deng, W.-M.,* Fujita, Y.* (2010). Involvement of Lgl and Mahjong/VprBP in cell competition. Plos Biology 8(7):e1000422.
Tamori, Y., & Deng, W.-M. (2013). Tissue repair through cell competition and compensatory cellular hypertrophy in postmitotic epithelia. Developmental Cell, 25, 350-363.
Palmer WH, Jia D, Deng, WM. (2014). Cis-interactions between Notch and its ligands block ligand-independent Notch activity. eLife. 3:e04415.
Tamori, Y., Suzuki E., Deng, W.-M. (2016) Epithelial Tumors Originate in Tumor Hotspots, a Tissue-Intrinsic Microenvironment. PLoS Biol. 14(9):e1002537.
Xie, G., Chen, H., Jia, D., Shu, Z., Palmer, W.H., Zeng, X., Hou, S.X., Jiao, R., Deng, W-M. (2017). The SWI/SNF complex protein Snr1 is a tumor suppressor in Drosophila imaginal tissues. Cancer Research, 77(4):862-873.
Tamori, Y., Deng, W.-M. (2017) Tissue-Intrinsic Tumor Hotspot: Terroir for Tumorigenesis. Trends in Cancer, 3, 259-268.