Senior Scientist - Next Generation Sequencing Expert

Bethesda, Maryland (US)
Competitive salary with comprehensive benefit package
June 21 2018
Position Type
Organization Type

The Laboratory of Pathology of the National Cancer Institute/National Institutes of Health (Bethesda, MD) is seeking a Senior Scientist with expertise in Next Generation Sequencing (NGS) to participate in our expanding clinical genomics program. In particular, the Laboratory of Pathology is planning to set up several NGS-based assays to identify genetic changes in clinical samples derived from cancer patients seen by the Intramural program of the National Cancer Institute. The Senior Scientist will provide oversight for design, development and implementation of NGS assays capable of detecting mutations, copy number changes and rearrangements in tumor samples. These NGS assays may include a large targeted panel, whole exome and/or whole transcriptome. Once the assays are established, the Senior Scientist will work with pathologists, bioinformaticians, technologists and support staff in the Laboratory of Pathology to receive and process samples, generate sequencing libraries, perform the sequencing runs, analyze data and generate clinical reports. In addition, the Senior Scientist will participate in quality assurance activities and regulatory management of these clinical genomics activities in the Laboratory of Pathology. The Senior Scientist will also interact with oncologists and scientists throughout the National Cancer Institute to plan larger research studies related to these genomic analyses of clinical samples, and to participate in the preparation of manuscripts resulting from these projects. Finally, the Senior Scientist will continue to innovate as this sequencing program progresses and will explore new methods and technologies for genome-wide assessment of tumor samples.

The requirements for this position are a PhD (or equivalent degree) in molecular biology, genetics or a related field. This position also requires substantial experience in the NGS field, either as part of a postdoctoral research training program or through direct participation in an NGS testing facility. Beyond an extensive background in NGS technology, the position requires experience with the application of bioinformatic and statistical tools and the analysis of genomic databases. Finally, strong written and oral communication skills as well as managerial and organizational experience are also required.

This Senior Scientist position is being recruited as a long-term contract position through a partnership with Kelly Government Solutions.  For further information and to apply for this position, please see the Kelly Career Network website at