Staff Scientist | Molecular Pathology Core

May 28 2018
Life Sciences
Position Type
Full Time
Organization Type
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

Requisition 13838

Staff Scientist | Molecular Pathology Core

Position Summary and Key Responsibilities:

A Staff Scientist position is available in Beckman Research Institute of City of Hope.

Performs pivotal role in the shared resources solid tumor and molecular pathology cores to support clinical translational research in the areas of multicolor immunohistochemistry, in situ hybridization, multicolor immunofluorescence assays, microRNA assays and image analysis. Performs new technology development and documentation as standard operating procedures under the direction of the core director.

Essential Functions:

  • Works on various solid tumor core and molecular pathology core projects as assigned, under direction of the molecular pathology core director and under the supervision of the Core Administrator.
  • Develop new multicolor immunohistochemical and multicolor immunofluorescence assays.
  • Develop in situ hybridization, microRNA and CyTOF FFPE assays
  • Establish image analysis methods to support the above assays.
  • Document all methods performed as standard operating procedures which will be approved by core director. SOPs will be implemented as offerings in the Cores.
  • Regular and timely attendance of meetings
  • Meet mutually agreed upon project goals; discuss project progress at weekly intervals with core director
  • Support scientific and technical staff in the lab
  • Stay up-to-date with the relevant literature
  • Enhances professional growth and development by participation in educational programs, workshops, conferences, and meetings.
  • Plays an active role in preparation of original manuscripts
  • Maintenance of records, standard operating procedures and other related duties as assigned or requested

Follows established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, includingadherence to theworkplaceCode of Conduct and Compliance Plan. Practices a high level of integrity and honesty in maintaining confidentiality.

Performs or participates in quality control, quality assurance, or quality improvement procedures.

Individuals appointed as staff scientists will receive a one-year fixed-term contract.

Minimum Education and Skills Required for Consideration:

Ph.D. in molecular biology or genetics preferred.

Minimum Experience:

  • 3+ years of relevant experience in performing and developing immunohistochemistry and immunofluorescence assays
  • 3+ years of experience with image analysis

Requirements, other:

  • Basic knowledge of histology, immunohistochemistry, immunofluorescence, RNA/DNA analysis methods, and image analysis.
  • Experience with statistical, spreadsheet, graphics and word-processing software packages.
  • Excellent verbal and written communication skills and the ability to interpret and summarize scientific results in a clear, concise, accurate manner.
  • Excellent teaching/training skills
  • Preferred Field of Expertise:Molecular Biology, genetics, immunohistochemistry, immunofluorescence.
  • Skills, other:Foster and promote a positive image and professional appearance.
  • Aptitude: Req./Pref. Collaborate on projects with others in the core and institution.
  • Compose presentations and manuscripts for publication.
  • Document methods, software and databases.
  • Troubleshoot problems.
  • Instruct/train others.
  • Machines/Equip: Req./Pref. Personal computers/High performance computers.
  • Computer peripheral equipment.
  • Working / Environmental Conditions:Atmosphere and environment associated with a laboratory.
  • Tobacco-free campus.
  • Exposed to material of a confidential nature on a regular basis.
  • Pressure due to multiple projects and deadlines.
  • Subject to regularly changing priorities and work assignments.
  • Likely exposure to infection from disease-bearing specimens.
  • Potential exposure to hazards of handling diseased organs/tissues.
  • Likely exposure to odorous chemicals and specimens.
  • Occasionally subjected to irregular hours.
  • Regularly exposed to the risk of blood borne pathogens.
  • Potential exposure to mutagenic substances.
  • Req. Protective Equipment Eye Protection/Goggles.
  • Face Protection.
  • Lab Coat.
  • Mask.
  • Non-Sterile Medical Gloves.
  • Physical Demands:Moderate physical effort (lift/carry up to 25 lbs.).
  • Occasional prolonged standing/walking.
  • Occasionally lifts supplies/equipment.
  • Manual dexterity and mobility.
  • Occasional reaching, stooping, bending, kneeling, crouching.
  • Depth Perception: ability to judge distance and space relationships.
  • Accommodation: ability to adjust vision to bring objects into focus.
  • Color Vision: ability to distinguish and identify different colors.
  • Works at tasks involving focused concentration.
  • Communication:Excellent organizational and oral/written communication and presentation skills

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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