Postdoctoral Fellow

Employer
Children's Hospital of Philadelphia
Location
Abramson Research Center, Children's Hospital of Philadelphia
Salary
Salary is compliant with NIH guidelines
Posted
May 08 2018
Position Type
Full Time
Organization Type
Academia

Postdoctoral fellowship in the study neuropsychiatric disease using human stem cells.

Dr. Stewart Anderson, https://stewandersonlab.research.chop.edu//, has a postdoctoral fellowship position available to start July 1 in his lab at the Children's Hospital of Philadelphia/University of Pennsylvania School of Medicine. We study the molecular and cellular mechanisms that govern the development of the mammalian forebrain. We use mouse genetics, forebrain slice and dissociated culture techniques, as well as mouse and human embryonic stem cells in transplantation experiments to study the fate determination of GABAergic interneurons of the cerebral cortex. In addition, we are using human stem cell-derived neurons, microglia, and astrocytes as tools for the study of gene-gene and gene-environment interactions in neuropsychiatric disease, including HIV, schizophrenia, and autism, and with some emphasis on mitochondria genetics.

This position focuses on the derivation of cortical interneuron subclasses from human stem cells, on the acceleration of their maturation in vitro and in vivo, and on their use in the study of and treatment for neuropsychiatric disorders.

Cell culture experience, preferably with human ES or IPS cells, is required. Additional experience in developmental neuroscience and basic molecular biology (i.e. RT-PCR, basic cloning, RNA-seq) is preferred.

Fluency in spoken and written English is required.

Applicants should submit a CV, statement of research interests, and contact information for three references to: Stewart Anderson by email: sande@pennmedicine.upenn.edu

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